Lecture 17: Basal Ganglia Flashcards Preview

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Flashcards in Lecture 17: Basal Ganglia Deck (17):
1

What is the basic function of the basal ganglia?

movement modulation

2

What separates the putamen and the caudate nucleus?

the internal capsule

3

Somatic Basal Ganglia

-Aka. Dorsal Basal Ganglia
-Consists of: Caudate, Putamen Globus Pallidus

4

Limbic Basal Gangli

-Aka. Ventral Basal Gangli
-Consists of: Nucleus Accumbens & Olfactory Tubercle, Ventral Pallidum

5

What type of neuron makes up 95% of the striatum?

spiny neurons

6

Describe the axon of spiny neurons.

It is long and leaves the striatum.

7

Describe the axon of aspiny neurons.

Short and do not leave the striatum.

8

What is another name for spiny neurons?

projection neurons

9

What is another name for aspiny neurons?

local circuit neurons or interneurons

10

Where do spiny neurons that produce ENK project to?

From the putamen to the GPe

11

Where do spiny neurons that produce substance P project to?

From the putamen to the GPi.

12

What do spiny neurons projecting to the substantial nigra predominately contain?

Substance P

13

What is the main function of the striatal neurons that project to the GPi?

promote limb movement

14

What is the main function of the striatal neurons that project to the pars reticulata of the SN?

promote eye movement

15

What is the main function of the striatal neurons that project to the pars compact of the SN?

regulate DA neurons

16

What is the main function of the striatal neurons that project to the GPe?

inhibit conflicting movement

17

Which type of striatal neurons possess D2 receptors?

Striato-GPe