Lecture 17: Clinical Pharmacology in Renal Disease Flashcards
1
Q
list the drugs which can cause post-renal acute kindey injury
A
- due to crystal formation or fibrosis
- methysergide
- acyclovir, indinavir
- sulfonamides
- triamterene
- methotrexate
- vitamin c in large doses
2
Q
which drugs can cause nephrotic syndrome?
A
gold
penicillinamine
NSAIDs
interferon
captopril
3
Q
what is the main cause of AKI in secondary care?
A
aminoglycoside antibiotics e.g. gentamicin (severe gram-negative sepsis) cause nephrotoxicity in 10-20% of therapeutic courses by causing proximal tubular injury leading to cell necrosis
