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EXCI 445 Sports Nutrition > Lecture 2 pptx > Flashcards

Lecture 2 pptx Flashcards

(72 cards)

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1
Q

gastrin Is secreted by ____ stimulates ____ Production and also stimulates secretion of _____ in the stomach

A

Stomach
HCL
Pepsinogen

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2
Q

secretin is secreted by which organ? and does what?

A

Small Intestine

Stimulates water and Bicarbonate secretion in pancreatic juice

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3
Q

CCK is secreted by which organ? and does what?

A

SI
secreting of enzymes into PJ
Gallbladder contractions
inhibits gastric motility

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4
Q

GIP ( gastric inhibitory peptide ) is secreted by which organ? and does what?

A

Small I

inhibits gastric motility and secretion

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5
Q

Glucogon like peptide 1 (GPL1)is secreted by which organ? and does what?

A

Illeum and colon

inhibits gastric motility and secretion

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6
Q

Guanylin is secreted by which organ? and does what?

A

Illeum and colon

causes removal of NaCl and water from feces

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7
Q

True or false. Gastrin and CCK compete for binding on Lower Esophageal Sphincter receptors.

A

True

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8
Q

True or false. Gastrin and CCK compete for binding on lower esophageal sphincter
receptors

A

True. They have opposite functions on the esophagus

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9
Q

Sucrose is disacch, comprised of which two sugars?

A

Sucrose -> glucose –fructose

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10
Q

Lactose

is disacch, comprised of which two sugars?

A

-> glucose –galactose

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11
Q 
Which one of these can cross the intestinal Lumen ( passively)?
i. Proteins
ii. Tripeptides,
iii. dipeptides
iv. LCFA
 v. MCFA
a all of the above 
b.i, v,
c. ii, iii iv
d ii, iii, v
A

d.

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12
Q

How are Fats broken down and absorbed through the lumen?

A
  1. Bile salts emulsify fatty acid droplets into smaller ones in the small intestine
  2. lipase released from the pancreas breaks down fat into FA, diaglerols, monoacyglycerol
  3. micelle encapsulates these bad bois for transport across the lumen
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13
Q

Most absorption of vitamins occurs in the ______ and _________. Does it occur by active transport or diffusion?

A

jejunum and ileum

Diffusion

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14
Q

Fat-soluble vitamins are?

A

A, D, E, K

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15
Q

Water-soluble vitamins are?

A

B vitamins and C

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16
Q

T or F B12 is water soluble therefore it can be absorbed easily though the lumen?

A

False. It requires IF (intrinsic factor; binding factor) to pass through epithelial wall to the blood stream

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17
Q

Intrinsic Factor is secreted by and is important for what?

A

secreted by gastric mucosa. It’s

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18
Q

folic acid requres which enzyme to be synthesized

A

Folic acid requires intestinal enzyme conjugase

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19
Q

True or false. minerals are generally well-absorbed in the intestine

A

False. Little absorption ( often need other substances to increase absorption) Loss of mineral in urine and feces

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20
Q

True or false 70% of absorption of water occurs in the small intestine. How does it occur?

A

false. 99% of absorption occurs in the small intestine via diffusion with an osmotic gradient

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21
Q

OsmolaRity: measure of [solute] /unit _______

simply, it is the ________of a solution

A

VOLUME (Osm/L)

concentration

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22
Q

Why is Osmolarity difficult to measure with consistency?

A

Δ volume w/ Δ temp/press, therefore more difficult to measure w/ consistency

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23
Q
  1. OsmolaLity: measure of [solute]/unit ______
  2. concentration of _____ dissolved in a solution
  3. True or false volume of solvent remains constant with / Δ temp/press, therefore reliable for measurement
A
  1. MASS (Osm/kg)
  2. particles
  3. True
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24
Q

Urine Osmolality: Normal 24-hr value in adults: _______ mOsm/kg
How will this number shift in a state of hypohydration vs. hyperhydration?

A

500-800 mOsm/kg
hypohydration: Increase
Hyperhydration: Decrease

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25
Gastric Emptying: High CHO (low fat) meals empties in ___ hr
4 hours
26
High FAT meal empties in ____ hr
6 hours
27
Why is a high FAT meal slower to empty?
Harder to breakdown, more complex bonds  Also abosobtion route
28
Which has a faster GE rate: food or fluid? | Why?
Fluid | Less time nand energy for mechanical breakdown
29
Gut-Microbiota-Brain Axis. Two systems that affect the body stress response during exercise: 1. 2.
1. SAM (sympatho-adrenomedullary) | 2. HPA (hypothalamus-pituitary axis)
30
Gut brain axis. Communication of stress response happens in which ways?
1. Release of NE, EP, glucocorticoids 2. Vagal nerve stimulation 3. Gut hormones (GABA, neuropeptide Y, domapine)
31
Gut microflora communication with brain and muscles how? At which cellular level do the gut microflora talk with the muscles
a .via byproducts of fermentation (ShortChainFattyAcids, tryptophan) b. mitochondria
32
True or false. Gut microflora may play a significant role in Control stress, anxiety, and depression.
true.
33
Is the gut micro flora active in Oxidative stress and inflammatory responses?
Yes
34
HOw is the gut microflura active in Energy metabolism?
microbiota-mitochondria crosstalk via SCFA's
35
Research has demonstrated that gut bacteria can modulate the HPA axis through which two ways?
``` synthesis of hormones and neurotransmitters, namely, serotonin dopamine GABA Tryptophan precursor ```
36
True or false. “Beneficial” bacteria may also down regulate production of cortisol and noradrenaline. State why this is or isn't beneficial
True. can help modulate stress response/ chronic stress
37
a ._________ (Bidirectional /unidirectional )communication exists between the gut microbiota and skeletal muscle. b. if unidirectional which way ( gut -> muscles or muscles ->gut)
a .Bidirectional
38
Bacteria digest _________in the gut, and also degrade _______
oligo- and monosaccharides | bile acids
39
Byproducts of the ________ via microbiota digestion are released into the blood stream, and affect signal transduction at the ______in skeletal muscle
biles acids and saccharides | level of the mitochondria
40
Secondary Bile acids: Modulate ________in mitochondria AND | Stimulate __ ____ and oxidation
transcription factors | FA uptake
41
What does this describe? End products of fermentation of non-digestible dietary fibres by intestinal bacteria
Short chain FA
42
What are some Short Chain Fatty acids? Which is the most beneficial one? What can they do?
Acetate, prioprionate, butyrate Buturate 1.Can modulate cellular inflammation and energy pathways 2. Can regulate skeletal muscle GLU and FA metabolism
43
True or false, resistance starches cannot Can be digested by bacteria in the gut and turned into SCFA
False. While they cannot be digested in the human body they can be digested by bacteria in the gut and turned into SCFA ( via fermentation)
44
Byturate production comes from a high fiber diet?
Yes
45
How does byturate carry out it's physiological functions?
Increased Mitochondrial activity G-protein coupled receptors Histone acylation Microbiome homeostasis
46
Probiotics: _______ and ______ strains demonstrate promising effects; sources include yogurt, kefir, supplements e.g. Bio-K
Bifidobacterium & Lactobacillus
47
True Or false? large dosages can be toxic
True
48
How does maintaining a ‘healthy gut’ benefit the physiological function and performance of an athlete?
better absorption and digestion better immune system function better functioning mitochondrial parameters increases uptake and oxidation of FA
49
``` Fill in the blank. Healthy GI Function: +/- no effect (_) digestion/absorption (_) neuro-endocrine balance (_) immune function (_) psychological wellness (_) endurance performance (_) faster recovery ```
+ all
50
What type of athlete most commonly experiences exercised-induced GI distress?
Long repetitive, high impact sport
51
What percentage of athletes experience GI distress?
25-70
52
``` The following are symptoms of upper or lower GI distress: Reflux/Heartburn Belching Bloating Stomach pain/cramps Nausea Vomiting ```
Upper GI Distress
53
``` The following are sympotomes of upper or lower gi ditress? Intestinal cramps Side ache Flatulence Urge to defecate Diarrhoea/loose stool Intestinal bleeding ```
lower
54
What are two most common compensation strategies used by athletes to minimize symptoms?
Don’t eat before competition | Have a bowel movement
55
Causes of GI Distress: 1. Changes in _____ 2. Splanchnic _____perfusion 3. Absorption and gut ____ 4. Junctions in epithelial wall may______, depends on _______[condition]
1. motility 2. hypo 3. permeability 4. break down, depends on protective factor of gut
56
Changes in gastric occur at ~ ___% VO2max: These changes include an increase or decrease in: __ pressure of LowerEsophagealSphincter __ duration, frequency and amplitude of esophageal peristalsis ___ rate Gastric Emptying __ transit time in small intestine ( __ peristalsis) __ transit time in the colon ( __ mucosal secretion dilutes colonic contents)
60-70%+ _ ↓ _ pressure of LowerEsophagealSphincter _↓_ duration, frequency and amplitude of esophageal peristalsis _↓__ rate Gastric Emptying _↑_ transit time in small intestine ( _↓_ peristalsis) _↓_ transit time in the colon ( _↑_ mucosal secretion dilutes colonic contents)
57
is overall oro-caecal transit time affected by exercise? | For most athletes?
No +
58
True or false. Exercise shunts BF to muscles. | Shunting is proportional to ______
a .true. To muscles for O2 and substrate transport and skin for thermoregulation b. exercise intensity
59
Δ in intestinal permeability (due to exercise ) is normally short-term or longer-term
short term
60
Strategies to prevent splanchnic hypoperfusion _____ exercise intensity (monitored via HR) _______ ______intensity during a single session Avoid use of _______(3-5x risk of GI issues) Modify nutrition intake, train the gut
1. Reduce 2. Gradually increase 3. NSAIDS
61
Nutritional strategies to prevent splanchnic hypoperfusion Avoid ingesting food ___prior When ingesting ________, avoid hyperosmolar fluids, use combination ________fluids/gels Consume healthy _____ post-recovery (may help to improve postexercise splanchnic BF, attenuate inflammation)
2-3hr CHO during exercise GLU+FRUC lipids
62
A chronic change in intestinal Permiability ( increase due to truama or NSAIDs use, etc) reults in which physiological outcomes?
Inflammation | Bacterial Translocation
63
True or false. Subtances like Citruline may help with Splanchic Hypoperfusion?
True. Via the NO pathway ( Vasodialation of Blood vessels) Glutamine and possibly arganine may help as well
64
Can you consume CHO during exercise without experiencing GI distress?
Yes, if its hypoosmolar | High [CHO] in a small, dense bolus might be tolerated
65
Tolerance in studies range from ___g CHO/hr to upwards of ___/min (___ g/hr), GLU+FRU (gel)
60 g/hr 1.4 g/min 84g/hr
66
Osmolality of blood serum: ______ mOsm
300
67
Which one of these are more likely to cause GI distress via delayed GE? Full cream – 275 mOsm Ice cream – 1150 mOsm Grape juice – 11700 mOsm
Grape juice. Super hyperosmolar
68
__________beverages (i.e. _____ mOsm) empty the stomach quickly (e.g. sports drinks ___% mix of sugars/polymers)
Iso-osmolar/isotonic ~300 mOsm 6-8%
69
Hyperosmolar Beverages Side effects??
- Gastric discomfort - Vomiting (even at 8% [CHO]; sensitivity is individual) - Osmotic diarrhea (if consumed in large amounts or just prior to competition)
70
True or false? Repeated ingestion of slightly increased volumes of food and drink during exercise can slightly increase GE rate.
True. it takes about 20s
71
Why must Gut training practiced during training must remain same during competition
Consumption of ‘unfamiliar’ fluids/food can double risk of GI symptoms
72
repetitive torso movement/twists, bouncing and after recent ingestion of fluid/food can lead to __________
ETAP (exercise-induced transient abdominal pain) | --> Aggravation of peritoneum and translocation of peritoneal fluid

EXCI 445 Sports Nutrition (4 decks)

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