Lecture 2: Skeletal System Flashcards

1
Q

Rigid materials

A
  • Resist stress without much deformation

- e.g. bone, keratin, dentin, enamel

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2
Q

Tensile materials

A

Resist being pulled on

E.g. silk, collagen

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3
Q

Pliant materials

A

Must deform in order to function properly

E.g. cartilage, mucus, synovial fluid

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4
Q

Stress

A
  • Force applied per unit area

- measured in pascals

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5
Q

Tensile stress

A

Tension, pulling

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6
Q

Compressive stress

A

Compression, pushing

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7
Q

Strain

A

Deformation caused by applied stress

Change in length divided by original length

Dimensionless

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8
Q

Stress-strain curve

A

The slope of the curve is a measure of stiffness

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9
Q

Elastic region

A
  • up to yield point

- item will return to original length

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10
Q

Plastic region

A
  • past yield point

- item changes shape permanently

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11
Q

Elastic material

A

Linear relationship between stress and strain

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12
Q

Viscoelastic material

A

Nonlinear relationship between stress and strain

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13
Q

Safety factor

A

Strength / typical load

E.g. failure stress / typical stress

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14
Q

Energy

A

Energy stored/put in when a stress is applied is proportional to area under the curve

Energy can be recovered when stress is relieved (only a portion recovered in viscoelastic material)

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15
Q

Functions of the skeleton

A
Leverage/movement
Support
Protection
Storage
Blood cell formation
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16
Q

Bone cells

A

Osteocytes: transport metabolites, sense mechanical stress, communication
Osteoblasts: deposition
Osteoclasts: resorption

17
Q

Cortical bone tissue

A

Compact, very dense
Outer layer
Stiff and strong

18
Q

Cancellous/trabecular bone tissue

A
  • Spongy, very porous
  • Inner layer
  • Trabeculae adapt to direction of loading and add strength
  • High energy absorption, not as strong as cortical tissue
19
Q

Bone tissue composition

A

25-30% water weight

60-70% minerals/collagen

20
Q

Bone minerals

A

Provide compressive strength and rigidity (calcium and phosphate)

21
Q

Bone collagen

A

Provides tensile strength & flexibility (protein)

22
Q

Ossification

A

Formation of bone by activity of osteoblasts and osteoclasts

23
Q

Wolff’s Law

A

Bone grows or remodels in response to forces or stresses upon it

24
Q

Appositional growth

A

Growth in diameter is controlled by the amount of mechanical stress and gravity placed on bone

25
Deposition
Osteoblasts | Response to increased stress (weight-bearing exercise)
26
Resorption
Osteoclasts | Response to decreased stress (disuse, immobilization, microgravity)
27
Osteoporosis
Resorption exceeds deposition of bone | too many holes, increased risk of fracture
28
Bones and physical activity
- Bones require mechanical stress to grow and strengthen | - loading -> deposition -> increased density
29
Anisotropic property of bone
Response depends on the direction of load application
30
Viscoelastic properties of bone
Response depends on rate and duration of loading
31
Loads applied to bone
Compression, tension, shear, bending
32
Cartilage
- Firm, flexible tissue - no blood supply or nerves - nourished by fluid within joint - reduces contact stress
33
Articular/hyaline cartilage
- covers joint ends at articulation - 60-80% water - contains collagen and proteoglycan
34
Fibrocartilage
- found where articular cartilage meets tendon/ligament - improves fit between bones - serves as intermediary between hyaline cartilage and other connective tissues
35
Ligaments
Fibrous CT, connects bone to bone - consists of collagen, elastic, and reticulin - viscoelastic
36
Types of synovial joints
``` Hinge: interphalangeal Pivot: radioulnar Condylar: knee Ellipsoid: metacarpophalangeal Saddle: intercarpal Ball and socket: shoulder ```