Lecture 2.5 Flashcards

(26 cards)

1
Q

What is the primary purpose of food and its digestion?

A

Energy production (ATP), nutrient supply, thermoregulation, storage of energy, and building blocks for DNA, proteins, and cell membranes.

Food is essential for life, providing energy and nutrients necessary for various bodily functions.

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2
Q

What role do vitamins play in the body?

A

Cofactors for enzymes

Vitamins assist in biochemical reactions as enzyme cofactors.

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3
Q

What is the role of ions in the body?

A

Maintain normal ion gradients, biological salts in some proteins

Ions are essential for various physiological processes, including nerve impulse transmission.

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4
Q

What is the temporary energy storage during fasting?

A

Glycogen, fat stores, protein stores

These stores provide energy when food intake is low.

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5
Q

What is the primary fuel used for 90% of the body’s energy needs?

A

ATP production

ATP is the main energy currency of the cell.

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6
Q

What are the four processes of the digestive system?

A
  • Digestion
  • Absorption
  • Motility
  • Secretion

These processes work together to break down food and absorb nutrients.

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7
Q

What happens in the mouth during digestion?

A

Enzymatic and mechanical break-up of food begins

The mouth prepares food for further digestion by increasing its surface area.

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8
Q

What is the role of saliva in digestion?

A
  • Softens and moistens food for swallowing
  • Enzymatic breakdown increases food SA
  • Defense against bacteria/viruses

Saliva contains enzymes like amylase and lipase that aid in digestion.

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9
Q

What does amylase do?

A

Breaks down large carbohydrate starch molecules into smaller fragments

Amylase is crucial for carbohydrate digestion.

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10
Q

What is the function of lipase in saliva?

A

Breaks down triglycerides into free fatty acids

Lipase facilitates the digestion of fats.

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11
Q

What occurs in the stomach during digestion?

A
  • Mechanical break-up of food
  • Attack by HCl and pepsin
  • Generates small peptides and amino acids

The stomach uses acid and enzymes to further digest food.

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12
Q

Why doesn’t the stomach digest itself?

A

To prevent extreme pain and damage to the stomach lining

Protective mechanisms are in place to safeguard the stomach.

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13
Q

What is a mucous barrier?

A

A viscous layer that protects the stomach lining

This barrier is crucial for preventing damage from stomach acid.

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14
Q

What are zymogens?

A

Inactive enzyme precursors stored in chief cell granules

Zymogens are activated only at low pH to prevent premature digestion.

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15
Q

What happens in the small intestine?

A
  • Neutralisation of acid
  • Motility and enzyme attack
  • Absorption of nutrients

The small intestine is where most digestion and absorption occurs.

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16
Q

What is the role of bicarbonate in the small intestine?

A

Helps neutralise acidic chyme from the stomach

This neutralisation is essential for the proper functioning of intestinal enzymes.

17
Q

What are plicae circulares?

A

Permanent folds in the small intestine that increase surface area

These structures enhance nutrient absorption.

18
Q

What are villi?

A

Tiny, finger-like projections that cover the inner lining of the small intestine

Villi further increase the surface area for absorption.

19
Q

What are microvilli?

A

Even smaller hair-like structures on each villus

Microvilli significantly enhance the absorptive surface area.

20
Q

What is a problem associated with absorption in the small intestine?

A

Diverticulitis, Coeliac disease, Crohn’s disease

These conditions can affect nutrient absorption and overall digestive health.

21
Q

What molecules cannot penetrate the phospholipid bilayer?

A

Polar, charged, and large molecules

The bilayer’s oily nature prevents these substances from crossing easily.

22
Q

How are monosaccharides absorbed in the small intestine?

A

Through specific transport proteins in the bloodstream

Monosaccharides are the absorbable units of carbohydrates.

23
Q

What happens to proteins after digestion?

A

Absorbed mostly as free amino acids, with some di and tripeptides

Amino acids are essential for various bodily functions.

24
Q

Where is iron primarily absorbed?

A

In the small intestine, specifically duodenum and upper jejunum

Iron absorption is critical for preventing anemia.

25
What is the function of enteric coatings on drugs?
Protect drugs in the stomach and release them in the duodenum ## Footnote Enteric coatings ensure that drugs are not degraded by stomach acid.
26
Why is surface area important in digestion?
Larger surface area increases the efficiency and speed of digestion and absorption