Lecture 3. aMPV, IB, ILT, AE, Reovirus Infection, malabsorption syndrome

Question 1

Avian metapneumoviral diseases

Answer 1

Turkey: avian (Turkey) Rhinotracheitis (ART/TRT)
Chicken: Swollen head syndrome (SHS)

Secondary bacterial infections (particularly E.coli)

In turkey and chicken breeders, the respiratory phase of the aMPV infection can be subtle and the drop in egg production that follows may be the only observed clinical sign

Question 2

TRT — ?

Answer 2

Turkey rhinotracheitis

Question 3

SHS — ?

Answer 3

Swollen head syndrome

Question 4

What is the pathogen of aMPV?

Answer 4

Paramyxoviridae family
Pneumoviridae subfamily
Metapneumovirus genus
-ss RNA, enveloped

aMPV - A, B, C, D subgroups - antigenic and genetic differences

Question 5

How infection by aMPV happens?

Answer 5

• direct contact (with the virus shed in the nasal and tracheal discharge)
• aerogenous way, aerosol inhalation

aMPV are fragile in the environment and are easily inactivated

Question 6

aMPV. Pathogenesis

Answer 6

Virus replicates in the epithelial cells of the upper respiratory tract
- replication cycle is very fast
- replication induces increased mucous production in the airways
- virus leaves the epithelial cells in short time and is shed mixed with the mucous