Lecture 31. Breathing and Ventilation Flashcards

(31 cards)

1
Q

What are the three phases of rhythmic breathing?

A

Inspiration - Active: Initiated by activation of the nerves to the inspiratory muscles
Post-Inspiration - Active: Recruitment of post-inspiratory muscles
Expiration - Passive: Inspiratory muscles relax and lungs recoil
– Active: activation of expiratory muscles

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2
Q

What do inspiratory muscles do?

A

Contract to draw air into the lungs and create normal breathing

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3
Q

What is the most important inspiratory muscle?

A

Diaphragm
Asymmetrically innervated
70% of your Tidal volume

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4
Q

What do post-inspiratory muscles do?

A

Slow diaphragm recoil and coordinate orofacial movement

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5
Q

When do expiratory muscles become active?

A

In times of high demand to increase tidal volume

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6
Q

What does contraction of the tongue support?

A

Supports the airway and reduces resistance during inspiration and expiration

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7
Q

What three types of plural membrane make up the thorax?

A

Costal parietal pleura
Mediastinal parietal pleura
Diaphragmatic parietal pleura

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8
Q

What is the visceral pleura?

A

A thin layer of epithelium covering each lung

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9
Q

What is the parietal pleura?

A

Lines inner surface of the walls of the thorax

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10
Q

What is the pleural cavity?

A

Maintains a partial vacuum which helps keep the lungs
expanded

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11
Q

What is the intrapleural fluid?

A

Allows pleurae to slide over one another

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12
Q

What generates pressure within the pleura?

A

Differential set points of muscles and lungs

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13
Q

What is the transpulmonary pressure (Pₜₚ)?

A

Difference in pressure between the inside and outside of the lungs within the thorax

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14
Q

What is the intrapleural pressure (Pᵢₚ)?

A

The pressure outside the lungs in the thorax

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15
Q

What is the alveoli pressure (Palv)?

A

The pressure inside the lungs is the air pressure inside the alveoli pressure

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16
Q

What keeps the lungs inflated?

17
Q

What causes pneumothorax (collapsed lung)?

A

Air in the plural cavity

18
Q

What is Boyle’s law?

A

Predicts that if the volume inside the lungs is
changed, pressure inside the lungs will also change

19
Q

What generates air movement in the lung?

A

Alveolar pressure

20
Q

What alters trans-pulmonary pressure to draw air into the lungs?

A

Inspiratory muscle contractions

21
Q

What alters trans-pulmonary pressure to push air out of the lungs?

A

Expiratory muscle contractions

22
Q

What is the exchange of gases in alveoli and tissues dependent on?

A

Partial pressures O₂ and CO₂

23
Q

What is Dalton’s Law?

A

In a mixture of gases, the pressure exerted by each gas (the partial pressure) is the pressure that the gas would exert if it were the only gas in the volume occupied by the mixture

24
Q

What determines atmospheric pressure?

A

Patm = PN₂ + PO₂ + PCO₂ + PH₂O = 760 mm Hg

25
What is anatomical dead space?
Volume of gas within the conducting airways Increases PCO₂ in the alveoli
26
What is physiological dead space?
Volume of gas not involved in gas exchange The two are almost equal in healthy lungs
27
When does net diffusion of a gas occur?
From a region where its partial pressure is high to a region where it is low
28
How is oxygen in the blood primarily transported?
On haemoglobin
29
What is the Bohr effect?
Carbon dioxide (CO₂) shifts the haemoglobin saturation curve to the right causing O₂ to dissociate from haemoglobin
30
How is CO₂ predominantly transported in the blood?
As bicarbonate ion
31
When does carbon monoxide poisoning occur?
Haemoglobin has an affinity for CO that is 210 times greater than its affinity for O₂, preventing the unloading of O₂ onto tissues