Lecture 4 - Bone structure & function Flashcards

(27 cards)

1
Q

one function of bones is detoxification

TRUE / FALSE

A

TRUE

Bone tissue can take up harmful heavy metals from the bloodstream that pose a risk to soft tissue

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2
Q

how many cells make up the cellular component of bone tissue?

A

four

these are the osteogenic cells, osteoblasts, osteocytes and osteoclasts

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3
Q

what are the differences between compact and spongy bone?

A

compact bone is dense, uniform in appearance and makes up ~80% of bone tissue

whereas spongy bone is less dense, has a messy structure and mostly makes up the inside the bone

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4
Q

what hormone can bone tissues secrete?

A

osteocalcin

this is an example of the endocrine role that bone tissue can play

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5
Q

the five main functions of bone tissue are

storage
blood cell formation
acid/base balance
detoxification
endocrine role

TRUE / FALSE

A

TRUE

bones can store several minerals including calcium, phosphate, growth factors as well as adipose tissue

blood cell formation occurs within the red/yellow bone marrow of bone tissue

bone tissue can take up/release protons and bicarbonate ions that impact blood ph

bone tissue can take up heavy metals that pose a risk to soft tissue

bone tissue can release the hormone osteocalcin

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6
Q

what is the role of osteoblasts?

A

osteoblasts secrete the organic component of the matrix - this causes cells to become trapped, forming the osteocytes

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7
Q

osteocytes can dissolve bone tissue

TRUE / FALSE

A

FALSE

it is the osteoclasts that dissolve and reabsorb bone tissue by secreting acids and enzymes

this is vital for repairing, remodelling and adapting the bone tissue

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8
Q

the Acellular component of bone tissue consists of the mineral matrix and the osteoid matrix

TRUE / FALSE

A

TRUE

the mineral matrix, also known as the inorganic matrix makes up ~70% of bone tissue

the osteoid matrix, also known as the organic matrix, consists of ~30% of bone tissue

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9
Q

what is the main component of the mineral matrix?

A

calcium phosphate

this CaPO4 forms very hard hydroxyapatite crystals that provide strength to the bone tissue

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10
Q

the osteoid component of bone tissue consists of four different cells

TRUE / FALSE

A

FALSE

the osteoid component, also known as the organic component consists entirely of collagen

this ensures the bone tissue is slightly flexible, otherwise the bone would be highly susceptible to snapping

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11
Q

sutural bones are typically cuboidal in shape

TRUE / FALSE

A

FALSE

sutural bones are only formed when two bones in the skull are sutured together - these are usually narrow and flat

short bones and sesamoid bones are examples of bone types that are usually cuboidal in shape

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12
Q

what is a sesamoid bone?

A

a sesamoid bone is a type of short bone that is situated on a tendon

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13
Q

an example of a flat bone is the vertebrae

TRUE / FALSE

A

FALSE

the vertebrae are a type of irregular bone as they have no obvious shape

a flat bone is typically narrow and flat compared with other bone types

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14
Q

the diaphysis of long bones contains mostly spongy bone

TRUE / FALSE

A

FALSE

the diaphysis consists of mostly compact bone with a central bone shaft

the central bone shaft can contain either red or yellow bone marrow

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15
Q

name the membrane that surrounds long bones

A

periosteum membrane

this membrane provides the bone tissue with a blood and nerve supply

the membrane is connected to the compact bone by sharpey fibres

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16
Q

what is the role of articular cartilage?

A

articular cartilage surrounds the ends of bones that form joints

its main role is to cushion the bone ends

17
Q

the epiphyseal plate is a remnant of the epiphyseal line from childhood

TRUE / FALSE

A

FALSE

it is the epiphyseal line that is the remnant of the epiphyseal plate

this epiphyseal plate played a role in growth during childhood

18
Q

name the cells that make up cartilage bones

A

chondrocytes

these cells begin to break down and calcify during endochondrial ossification

19
Q

place these phrases in order for the process of endochondrial ossification

  1. these osteoblasts begin producing spongy bone until the entire diaphysis is filled
  2. osteoblasts begin producing the bone tissue, these
    osteoblasts also migrate to the centre, forming the primary ossification centre
  3. after birth, secondary ossification centres form in each of the epiphysis
  4. blood vessels infiltrate the bone and the perichondrium surrounds the bone
  5. chondrocytes in the centre of the cartilage bones begin to break down and calcify
  6. the perichondrium begins differentiating into the periosteum, this region then forms osteoblasts
A

the correct order is 5, 4, 6, 2, 1, 3

20
Q

what are the three ways joints can be classified in terms of functionality?

A

functionally, joints are classified into synarthroses, amphiarthroses and diarthroses

synarthroses are completely immovable, amphiarthroses offer little movement and diarthroses are freely moveable

21
Q

fibrous joints are when two bones are separated by a fluid filled cavity

TRUE / FALSE

A

FALSE

fibrous joints are when two bones are seperated by fibrous tissue

a fluid filled cavity separates two bones in a synovial joint

22
Q

synchondrosis and symphysis are two examples of fibrous joints

TRUE / FALSE

A

FALSE

these are examples of cartilaginous joints, synchondrosis is the joint between the first rib and sternum and symphysis is the joint between vertebrae

23
Q

name three examples of fibrous joints

A

examples of fibrous joints include sutures, gomphosis and syndesmosis

sutures are when two skull bones are connected, gomphosis is the connection between teeth and the socket, syndesmosis are connections using slightly longer fibres that facilitate some movement

24
Q

ball and socket joints offer the most movement

TRUE / FALSE

A

TRUE

ball and socket joints are a type of synovial joint that offer a multi-axial range of movement

25
there are four main features of a synovial joint, these are the articular cartilage, articular capsule, ligaments and the joint cavity TRUE / FALSE
TRUE the articular cartilage cushions the bone ends while the articular capsule is made up of the fibrous capsule and inner synovial membrane ligaments hold the bones in place and prevent them dislodging, while the joint cavity is filled with synovial fluid that also provides cushioning
26
pivot joints occur when one bone spins on top of another TRUE / FALSE
TRUE an example of this is in the arms, where the humerus holds the radius and ulna together
27
hinge and saddle joints provide similar levels of movement TRUE / FALSE
FALSE hinges provide movement in only one direction, making them uniaxial condylar and saddle joints provide similar movement, they allow for backwards/forwards and side to side movement