Lecture 4: Embryogenesis Flashcards

1
Q

What field studies development between fertilization and birth?

A

embryology

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2
Q

What field studies embryonic and other developmental processes such as stem cell biology and regeneration?

A

developmental biology

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3
Q

What % of embryos are spontaneously aborted?

A

50%

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4
Q

what % of live born children have a birth defect?

A

3-6%

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5
Q

what % of births are premature in the USA? Is this higher or lower than the % of premature births in other developed countries?

A

~12%

higher

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6
Q

what are the two leading causes of infant mortality?

A

premature births

birth defects

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7
Q

Weeks _____ of human pregnancy are known as embryogenesis (also called organogenesis), when_______ are established

A

1-8

embryogenesis

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8
Q

What are organ primordia?

A

organs in earliest recognizable stage of development

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9
Q

The embryonic period is followed by the ______ of continued _______ and ______

A

fetal period
differentiation
growth

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10
Q

What are Carnegie Stages of embryogenesis based on? What are they not based on?

A

based on external features

not based on chronological age nor size

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11
Q

How many Carnegie stages are there?

A

23

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12
Q

What is postovulatory age refer to? what terms does it replace?

A

maturity of embryo - length of time since last ovulation before pregnancy
better than gestation, pregnancy, conception

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13
Q

In the ____ week of embryogenesis, the zygote undergoes division to become a _____ and then a _______

A

first
morula
blastocyst

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14
Q

What structure implants into the uterine wall?

A

blastocyst

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15
Q

The oocyte is fertilized in the ______ region of the ________

A

ampullary

uterine tube

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16
Q

what ploidy is the zygote?

17
Q

how does the female anatomy help the sperm reach the oocyte?

A

muscular contractions of the uterus and uterine tube toward the ovary

18
Q

without fertilization, the oocyte degenerates _____ after ovulation

19
Q

what kind of division do the oocyte and sperm undergo after fertilization?

20
Q

during cleavage mitotic divisions of embryogenesis, cells are known as _______

A

blastomeres

21
Q

during cleavage mitotic divisions of embryogenesis, ______ segregates ______ fomr ______

A

compaction
inner cells
outer cells

22
Q

____ days after fertilization, the ____-cell morula is formed

A

3 days

16 cell

23
Q
How many hours post-fertilization...
2 cell stage
4 cell stage
16 cell stage
late morula stage
A

2 cell stage - 30hrs
4 cell stage - 40hrs
16 cell stage - 3 days
late morula stage - 4 days

24
Q

What stabilizes the cells during compaction of embryogenesis?

A

tight junctions between outer cells

seals off inner cells

25
What does the blastocyst turn into?
Inner Cell Mass | Trophoblast
26
What does the inner cell mass turn into?
Amnionic ectoderm | Embryonic epiblast
27
What does the amniotic ectoderm turn into?
Nothing
28
What does the embryonic epiblast turn into?
Embryonic ectoderm | Primitive streak
29
What does the primitive streak turn into?
Embryonic endoderm | Embryonic Mesoderm
30
What do the Embryonic Ectoderm, Endoderm, and Mesoderm turn into?
Nothing
31
What does the Hypoblast turn into?
Extraembryonic endoderm
32
What does the extraembryonic endoderm turn into?
Yolk sac
33
The yolk sac and embryonic mesoderm combine to form _______
extraembryonic mesoderm
34
What does the trophoblast turn into?
Cytotrophoblast
35
What does the cytotrophoblast turn into?
Syncytiotrophoblast