Lecture 5 Flashcards
Spinal Cord General
- Function
- Reliance on Brain
- Pathway for what?
- Link brain and body
- Exhibits some functional independence from brain
- Sensory and motor impulses, reflexes.
Spinal Cord Development
- Developts from what layer of tissue?
- See Study Sheet #1 and Label A, B, C, D, E
- Function of the notocord?
- Ectoderm
- A = neural plate, B = notocord, C = neural tube, D = neural crest cells, E = epidermis
- Induce neuroectoderm to form neural tube
Spinal Cord Development
- Gray matter: location and what it is
- White matter: location and what it is
- In the center of the spinal cord, makes up horns. It is a concentration of cell bodies.
- Surrounds gray matter, is axons.
Spinal Cord Development
- See Sheet #2 and label A - G
- A = Dorsal alar plate, B = Ventral basal plate, C = central canal, D = ependymal layer, E = mantle, F = marginal layer, G - sulcus minitans
Spinal Cord General
- Dorsal Pathway carries what type of information?
- Ventral Pathway carries what type of information?
- Sensory
- Motor
Spinal Cord Anatomy
- See sheet # 3 and label A - F
- A = Central canal, B = dorsal gray column (horn), C = tracts (white matter), D = lateral gray column (horn), E = ventral gray column (horn), F = tracts (white matter)
Spinal Cord Development
- See # 4 and label A -
- A = Central cavity, B = Neuroepithelial cells, C = gray matter, D = white matter, E = Alar plate, F = Basal plate, G = dorasl root ganglia
Spinal Cord Development
- Dorsal root ganglia form from?
- Briefly review the development of sensory neurons in the alar plate.
- Briefly review the development of motor neurons in the basal plate.
- Crest cells
- This is all sensory information. As crest cells in this area develop into dorsal root ganglia, they send projections to the body and to the spinal cord to act as information relays.
- The motor neurons in the basal plate just send out projections to the body. They do not need to grow into the spinal cord because they don’t need any information coming back to the spine.
Anatomy of the Spinal Cord: General
- General shape
- Two enlargements
- # of spinal nerves
- Long flattened cylinder
- Cervical in the neck and lumbar in the thoracic region
- 31
Spinal Cord Development
- General CNS structure at 49 days after fertilization
- General CNS structures at 3 months old
- Brain is sectioned
- Two enlargements visible, spinal cord vs brain is distinguishable, most CNS-body neuronal connections are in place
Anatomy of the Spinal Cord: Cervical Region
- What is the defining part of this region?
- What are the two parts of this and what do they do?
- Cervical enlargement
- Cervical plexus: innervates the neck, Brachial plexus: innervates the should and upper limbs
Anatomy of the Sinal Cord: Thoracic Region
- Thoracic sympathetic outflow (very general)
- Intercostal nerves: what are they?
- involves leteral horns of the spinal cord
- Long single pairs of spinal nerves that go between ribs from the spinal cord
Anatomy of the Spinal Cord: Lumbar Region
- Lumbar sympathetic outflow
- Lumbosacral enlargement: two components and what they do.
- Will be covered in the future, just wanted to include it on this card.
- Lumbar plexus and Sacral plexus merge together to innervate glutes and lower limbs
Anatomy of the Spinal Cord: Sacral Region
- Sacral parasympathetic outflow
- Comes from cranial nerves and a small sacral part of the spinal cord. Just know that this exists.
Anatomy of the Spinal Cord: Meningeal Coverings
- Dura mater
- Arachnoid mater
- Pia matter
- Outermost layer, durable
- Middle layer, closely adhered to the dura mater
- Directly against spinal cord tissue
Anatomy of the Spinal Cord: Meningeal Coverings
- What does the pia mater consist of?
- Function of one of those?
- Denticulate ligaments and Filum terminalis
- The Denticulate ligament is a projection of pia mater that anchors the spinal cord
Anatomy of the Spinal Cord: Meningitis
- Results from
- Symptom related to this lecture
- Inflammation of the linings of brain and spinal cord
- Stiff neck
Anatomy of the Spinal Cord: Spaces Between Meninges
- Space between dura and arachnoid mater
- Space between arachnoid and pia mater
- Where is CSF found?
- Subdural space
- Subarachnoid space
- Subarachnoid space
Anatomy of the Spinal Cord: Processes
- Anterior Rootlets: location and what they converge on
- Posterior Rootlets: location and what they converge on.
- In ventral part of the spinal cord, converge on the ventral root.
- Dorsal to the anterior rootlets, come out of dorsal portion of spinal cord. Converge on the dorsal root ganglion. Involved in sensory information
Anatomy of the Spinal Cord: Processes
- Four processes of the spinal nerve
- Anterior ramus, posterior ramus, gray rami rami communicantes, white rami communicantes
Anatomy of the Spinal Cord
- What is the difference between roots and rami?
- Roots only contain EITHER motor OR sensory neurons. Rami contain both.
Anatomy of the Spinal Cord: Other Features
- Conus Medularis
- Cauda Equina
- Epidurals
- Forms a little point, off of which you have the cauda equina. It is located between L1 and L2
- After the conus medularis, this is where spinal nerves splay out like a horses tail.
- Best done beneath the conus medularis (L2). So most epidurals are done between L3 and L4
Anatomy of the Spinal Cord: Other Features
- Filum terminale
- A pia mater structure that goes down the length of the spinal cord and anchors in the base of the sacrum.
Anatomy of the Spinal Cord: Differential Growth of Spinal Column and Spinal Cord
- How does spinal cord growth vs spinal column growth impact the anatomy of adults vs newborns?
- What are the clinical implications of this?
- The location of the Conus Medullaris in a newborn is lower than it is in an adult. It will recess cranially in adults.
- If you ever needed to do a CSF withdrawal of a newborn, you would have to go lower than in an adult so as not to nick the spinal cord.




