lecture 7: minerals Flashcards

1
Q

major minerals

A

amounts exceeding 5g in the body
- calcium, phosphorus, potassium, sulfur, sodium, chloride, magnesium
(SNaP CaKCl Mg)

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2
Q

trace minerals

A

less than 5 grams in the body
- iodine, iron, zinc, selenium, fluoride, chromium, copper, other

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3
Q

calcium roles

A

integral part of bone structure
bone serves as calcium reserve
regulated by hormones
- other 1% is in body fluids: muscle contraction/relaxation, nerve function, blood clotting

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4
Q

bone formation calcium

A

hydroxyapatite: calcium + phosphorus = Ca3(PO4)2, add collagen

fluorapatite: displaces “hydroxy” part; fluoride makes bone stronger, resists resorption

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5
Q

calcium absorption

A

increased when calcium is needed
- amount absorbed in intestine increases

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6
Q

bone loss

A

happens around 25-30, 10 yrs after peak bone mass/height

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7
Q

osteoporosis

A

pediatric disease with gerontological effects

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8
Q

how to protect against bone loss

A

diet rich in calcium in early life

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9
Q

calcium sources

A

primarily milk and alternatives or fortified beverages
broccoli, leafy greens, legumes
avg canadian does not meet recommendations

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10
Q

calcium deficiency

A

adult bone loss - osteoporosis
in children - stunted growth, weak bones

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11
Q

calcium toxicity

A

quite rare
- constipation and kidney stones

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12
Q

phosphorous

A

2nd most abundant, associated w bones and teeth

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13
Q

phosphorus roles

A

maintain acid-base balance
part of DNA/RNA
part of metabolism - P in NADP
assists enzymes, vitamins in extracting energy = ATP
part of the phospholipids

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14
Q

phosphorus deficiency

A

doesn’t rly happen, easily met

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15
Q

phosphorus toxicity

A

calcification of soft tissues

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16
Q

phosphorus sources

A

animal proteins are best source
found in cola drinks

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17
Q

magnesium

A

50% bones, 1% fluid, rest in muscles, heart, liver, soft tissues
blood mg can b reg by taking it from bones or kidney reabsorption

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18
Q

magnesium roles

A

helps enzymes function
metabolism
muscle function
bone mineralization and resistance to tooth decay

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19
Q

magnesium deficiency

A

may occur from inadequate intake, vomiting, diarrhea, alcoholism, protein energy malnutrition
or
hospital clients on TPN and poor diets

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20
Q

magnesium sympt

A

muscle weakness
CVD, heart attack, HTN
symp rare tho inakes often below recommended

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21
Q

magnesium toxicity

A

may cause diarrhea, acid base imbalance
rare but fatal only w high intakes from supplements, mg salts, laxatives/antacids

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22
Q

magnesium sources

A

easily washes/peels away from foods in processing
totally unprocessed or slightly processed
vegetarian protein: legumes, nuts
whole grains, dark green veggies, seafood, chocolate

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23
Q

sodium role

A

fluid/electrolyte balance
acid-base balance
muscle contraction, nerve transmission

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24
Q

sodium deficiency

A

rare since foods are salty
can result from low sodium, kidney disease, heart failure diets
endurance athletes
hyponatremia: low blood sodium, headache, confusion, stupor, seizures, coma

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25
sodium body maintenance
- absorbed freely byb body and excess excreted by kidneys into urine - small amount lost in sweat - amount excreted in day = amount digested per day
26
RDA intakes for sodium********
AI (adequate intake): 1500mg (age 19-50) (UL) Tolerable upper intake level: 2300mg ppl eat more than UL approx 3400mg/day gen from processed food, soy sauce, MSG, flavouring, bread (surprisingly)
27
sodium sources
- junk food, bread, processed food, tomato dishes, soups, pasta, cheese (except swiss), meat dishes, sauces (anything seasoned) 75% processed food
28
blood pressure sodium
- high sodium associated w higher HTN, CVD, cerebral hemorrhage rates - more salt = higher bp and risk for CV diseases - some ppl sodium sensitive
29
reasons to reduce salt
- old ppl w/o HTN can die of stroke - lowering intake can lower bp to reduce risk of stroke - can cause congestive heart failure or make kidney problems worse - potentially cause stomach cancer
30
potassium
principle +'ve charged ion inside body's cells
31
potassium roles
maintenance of: fluid balance electrolyte balance heartbeat
32
potassium deficiency
reasonable diets provide enough K to prevent dangerously low k - heart failure from: fasting, severe diarrhea, eating disorders, etc - can make HTN worse normal intake is little over 50% of AI
33
potassium sources
- fresh, whole foods, fruits - processing reduces it - OJ, bananas, potatoes, tomatoes, avocados, strawberries, spinach, cantaloupes AVOID if u have chronic kidney disease
34
potassium toxicity
- SAFE unless u have chronic kidney disease - if injected to vein stops heart - OTC KCI pills - don't take unless doc tells u
35
chloride
major neg ion in body
36
chloride role
acid base balance electrolyte balance component of HCI
37
chloride sources
salt; added and naturally occuring
38
chloride deficiency
not possible
39
sulfur roles
synthesis of compounds w s - amino acids w S - cysteine, methionine*** - disulfide bonds w cysteine - antioxidants - thiamin, biotin
40
sulfur sources
protein containing food (in amino acids)
41
sulfur deficiencies
unknown
42
sulphur toxicity
diarrhea, not important
43
iodine
has been added to table salt to meet intakes
44
iodine roles
require thyroxine (hormone) made by thyroid gland to reg metabolism
45
iodine deficiencies
- enlarged thyroid - GOITRE*** - severe deficiency during preg - CRETINISM***; retardation - sluggishness - weight-gain
46
iodine toxicity
enlarged thyroid gland but decreased thyroid activity
47
iodine sources
- iodized table salt - seafood - depends on soil which has 1/2 day's intake since iodine is used to disinfect milking equipment
48
iron
most in body carried in proteins: HEMOGLOBIN: o2 carrier protein of RBCs in bloodstream MYOGLOBIN: o2 carrier protein of muscle cells
49
iron roles
carries oxygen and helps enzyme use o2 needed to make new cells, amino acids, hormones, neurotransmitters liver adds iron to new RBC's from bone marrow; recycled after 3-4 month in liver/spleen
50
iron loss
can b lost in nail clippings, hair cutting, skin shedding - significant if you lose from bleeding; GI bleeds
51
iron gain
only 10-15% from diet actually absorbed but amount can increase/decrease if: body supply diminished and needs it, or body supply abundant hard to readily get rid of iron
52
Free iron is...
a powerful oxidant, can damage cells
53
iron deficiency
absorption not compensating for loss or low dietary intake, in stages stage 1: decreased iron stores stage 2: depleted iron stores stage 3: iron deficient and anemic
54
iron deficiency anemia
more severe; depleted iron stores and low blood Hb
55
microcytic anemia
cells are smaller
56
hyperchromic
lighter red than normal
57
pica
craving non-foods; assoc w iron deficiency - you eat clay, soil, air freshener; shits bad for u and will inhibit iron absorption
58
risk factors of iron deficiency
being women (tend to eat less food and lose iron bc you bleed - menstruating or preg being an infant that isn't breastfed anymore, young child, adolescent most common nutrient deficiency
59
iron toxicity
hard to excrete once absorbed - iron overload defended against controlling iron absorption - genetic component: white ppl tend to continue to absorb iron even in excess CV infection: bacteria thrive on iron-rich blood vit c helps iron absorption
60
iron sources
preg women need supplement iron forms: heme-bound (animal flesh) or nonheme (plants) read meat, fish, poultry, shellfish, eggs - MEAT legumes, green leafy veggies, dried fruit
61
iron absorption
MFP factor: meat, fish poultry
62
Zinc
occurs in very small quantity in body
63
zinc roles
everything works w proteins in every body organ helps over 300 enzymes taste perception, wound healing, sperm production
64
zinc deficiencies
often misdiagnosed mild: impaired immunity, abnormal taste, abnormal vision in dark severe: affects growth, infections will worsen w malnutrition, wounds heal poorly, alters digestive sys
65
zinc risk groups
preg, poor, young, old, vegetarians
66
zinc toxicity
@ risk in supplements ***can block copper absorption/lower body's copper content*** can reduce HDL blood concentrations
67
zinc sources
meat, fish, poultry, milk and milk products plants not absorbed well; but some legumes and whole grains
68
selenium roles
antioxidant
69
selenium deficiencies
prostate cancer heart disease/keshan disease
70
selenium toxicity
w long term supplementation (nausea, ab pain, hair loss, nerve abnormalities)
71
selenium sources
normal diet of unprocessed foods; widely distributed - meats, shellfish, veggies in selenium rich soil
72
fluoride
not essential to life per say
73
fluoride roles
important for teeth - fluorapatite is resistant to decay
74
fluoride sources
fluoridated drinking water
75
fluoride deficiency
dental decay where fluoride is mising
76
fluoride toxicity
Fluorosis: Discolouration, pitting of tooth enamel during tooth development Irreversible once developed
77
chromium roles
Blood glucose regulation with insulin; regulate release glucose energy
78
chromium deficiency
Impaired Insulin Action*; results in diabetes-like condition - fixed with supplements Supplements however CANNOT cure actual diabetes
79
chromium sources
Widely distributed in food supply; unrefined foods, whole grains Meat, whole grains, vegetable oil
80
copper roles
Forming hemoglobin and collagen Can handle oxygen - enzymes depend on it, metabolism Also handles iron Superoxide dismutase: Unfucks free radical damage, is copper-dependent
81
copper deficiency
Excess zinc can interfere with copper absorption - deficiency Menkes disease: Absorbed but not released into circulation Disturbed growth and metabolism Impaired immunity, arterial blood flow in adults rare in severely malnourished infants
82
copper toxicity
Unlikely from foods; possible from supplementation Wilson’s Disease: Copper accumulates in liver/brain; treated with Zinc supplements Copper ring around the eye, pretty cool
83
copper sources
unimportant
84
osteomalacia
Vitamin D deficiency disease characterized by overabundance of unmineralized bone protein - Symptoms include bending of spine, bowed legs
85
osteoporosis
A reduction in bone mass in older people; the bone becomes porous and fragile 1/3 women and 1/5 men suffer from osteoporotic fractures; people w/ fractures may need LTC Get a diet rich in calcium early on in life to prevent osteoporosis later in life
86
bone breaks and use of tobacco + alc
Smokers have less dense bones and alcoholism = undernutrition, fall risk
87
DASH Diet
Dietary Approaches to Stop Hypertension - Can help both salt-sensitive and non-sensitive Achieves a lower blood pressure than restriction of sodium alone Involves greatly increased intake of vegetables and fruits Adequate amounts of nuts, fish, whole grains, low-fat dairy Occasional small portions of red meat, butter, high-fat foods/sweets Greatly reduces salt/sodium Results in progressively lower sodium and lower blood pressure as well Adding Mg, K, Ca, Protein, Fibre makes this drop even larger Ex., whole grains, fruits, veggies, seeds, nuts, legumes Low K intake raises blood pressure High K intake prevents and corrects HTN Physical activity also lowers BP