Lecture 8: Histology of the Small and Large Intestine Flashcards
Where are Brunner’s Glands found?
Only in the duodenum (submucosa)
Where are Vili of the small intestine shortest and longest?
- Longest in Duodenum
- Shortest in Ileum
In regards to the Plicae Circulares, where are they most numerous and where are they absent?
Most numerous: Jejunum and Proximal Ileum
Absent: Proximal duodenum and distal ileum
What do golblet cells do, and where do they increase?
- Secrete mucus
- Increase in number more distally along the GI tract
What is pictured here; what layer are they found in?
Peyer’s Patches; found in the Mucosa
What is encircled by the blue box; found most abundantely where?
Plicae Circulares; most abundant in jejunum and proximal ileum
Label A-C
A - Vili
B - Lamina Propria
C - muscularis mucosae
*At the bottom of the Vili lies the crypt with the bolded c.
Label the arrows from top to bottom
Top: Lumen of crypt
Stem Cell
Paneth Cell
Enterodendocrine cell
Label A-C
A) Circular layer
B) Myenteric Plexus
C) Longitudinal layer
What cell type are the arrows pointitng to?
Goblet Cells
What is the arrow labeled P; distinguishing feature?
Paneth Cells; Prominent Eosinophilic Apical granules
What are the role of Paneth cells?
Defensive funcion:
- Secrete lysozyme
- TNF-alpha
- Defensins
What is the structure denoted by E; distinguishing characteristic?
- Enteroendocrine (Neuroendocrine) Cells
- Cytoplasmic granules which are in a Subnuclear positon
What is the function of Enteroendocrine Cells?
Produce locally acting hormones that regulate GI motility and secretion:
- Gastrin
- CCK
- Secretin
What is the structure denoted by MF?
Stem Cell (Mitotic Factor)
What part of the small intestine is this and what are the distinguishing features?
- Duodenum
- Leaflike vili
- Brunner’s glands (submucosa)
What part of the small intestine is this and the distinguishing feature?
- Jejunum
- Finger-like vili
What part of the small intestine is this and what are the distinguishing features?
- Ileum
- Vili are short
- M cells
- Many Peyer’s patches in LP and submucosa
What are characterisitics of the large intestine mucosa?
- Simple columnar (microvili)
- NO vili
- Abundance of Enterocyttes and Goblet Cells
- Deep Crypts of Liebrkuhn
What are the arrows pointing to and where in GI tube are they found?
- Teniae Coli in Large Intestine (Muscuralis Externa)
Label these large intestine cell types from top to bottom.
- Enterocytes
- Goblet Cells
- Enteroendocrine Cells
What organ is this?
Veriform Appendix
What is this picture showing; how do you know?
Transition from the Retum –> Anal Canal
Rectum = Simple columnar w/ Goblet Cells
Anal Canal = Stratified Squamous
*Notice the tranisition at the pectinate line
Label all the arrows
