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lecture #9 Flashcards

(32 cards)

1
Q

Opium is from

A

opium poppy seeds

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2
Q

opium is a mixture of chemicals with the most prevalent being _____ , __________

A

morphine and codeine

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3
Q

derivatives of opium are known as

A

opioids

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4
Q

heroin

A

derivative of morphine by acetylation

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5
Q

buprenorphine

A

partial agonist, lessens euphoric effects

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6
Q

Methadone

A

opioid that behaves like heroin but with less euphoric effects and long acting

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7
Q

chronic pain

A

5th vital sign

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8
Q

abuse is

A

used for the feeling to get high

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9
Q

tolerance

A

effect of drug wears off, need more for the same effect

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10
Q

dependence has two types

A

psychological dependance cravings
physiological: withdrawal upon cessation.

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11
Q

what is hyperalgesia

A

heightened sensitivity to pain that occurs from opioid use

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12
Q

addiction

A

compusive use, despite harm

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13
Q

clinical effects of opioids

A

contains opoid receptors in the cerbral cortex for pain relief and medulla for euphoria (respiratory depression

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14
Q

potency is not as important as dose

A
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15
Q

dose rate importance example

A

oxycontin not meant to be chewed or crushed. need to reformulate into uncrushable

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16
Q

Naloxone

A

antidote for opioid sandoz, teva, perrigo competitive antagoism

17
Q

opioid withdrawal syndromes

A

piloerection (goose flesh) chills, V/N

18
Q

OWS can be treated with

A

methadone, buprenophrine

19
Q

small volitable products that makes distilled drinks distinct

20
Q

clinical effects of ethanol

A

abosptive, toxic, elimination

21
Q

legal limit

22
Q

drunk?

A

BAC via breath analyzer + FST

23
Q

how alcohol affects CNS

A
  1. change the fluid components of menbrane, haldane effect
  2. inhibits GABA receptor chloride channel complex
24
Q

sedatives

A

GABA chloride channel

25
melleby effect
acute tolerance tachyphylaxis
26
conventional benxo
xanax, valium
27
NPS benxo
etizolam
28
roofies
flunitrazwpam
29
special K
euhjpria, deep CNS depression
30
carisoprodol soma
muscle relaxant
31
sedative intoxication
mostly coma
32
antidote
flumazenil