Treatment of visc leish
Injections of pentostam and glucantime
Diagnosis of visc leish
- Take a spleen sample
2. Look for amastigotes
Old world visc leish.
- Sp
- Loc
- Vec
- Leishmania donovani
- Old world
- Phlebotomus sergenti
New world visc leish.
- Sp
- Loc
- Vec
- Leishmania
- New world - brazil
- Lutzomyia shannoni
Causes largely urban form of cuta leish
Leishmania tropica
What system does leishmaniasis infect?
Reticuloendothelial system
Pathology and symptoms of L. major
Inflammation at the site of infection and formation of a painful ulcer.
Causes Rural form of cuta leish
Leishmania major
New world leishmaniasis (sp)
- L. mexicana
- L. braziliensis
- L. chagasi
Old world leishmaniasis (sp)
- L. tropica
- L. major
- L. donovani
Diagnosis/treatment of L major
- Tissue scraping
- Look for amastigotes
Natural healing is best, but pentostam and glucantime injections can be administered.
Difference between diagnosing L. major and tropica.
Tropica - humans are a better host and there will be more amastigotes in the sample.
Country where L. major or tropica can be acquired
Saudi
Reservoir host for major and tropica
Rats
Diagnosis of muco leish
- Tissue sample
2. Look for amastigotes
Muco leish treatment
Injection or pentostam and glucantime
Main reservoir for muco leish
Small rodents
Control of brasiliensis
Difficult due to sylvatic nature.
