Leprosy Flashcards
(16 cards)
2 organisms that cause leprosy
Mycobacterium leprae and mycobacterium lepromatosis
Transmission of leprosy
Contact with infected persons nasal secretions and skin lesions
Contact with amadillos
Age at risk of leprosy
Bimodal
5~15
After 30
Genetic risk factors of leprosy
NOD2 gene
Rate of growth of mycobacterium leprae
12.5 days before it multiplies
Temperature most suitable for mycobacterium leprae
27-33 degrees.
Parts of the body affected by leprosy
Skin
Eyes
Nose
Larynx
Leonine facies
Thickened pinna
Loss of eyebrows
Facial nodules
Nerve involvement in subtypes of leprosy
Insidious in multibacillary
Subtypes of leprosy and their characteristics
Tuberculoid… 5 or less hypopigmented lesions .. well defined and early nerve involvement
Lepromatos- 6 or more symmetrical lesions..
leonine facies
Insidious nerve involvement
Borderline
Immune reactions in leprosy
Type 1- in borderline
Type 2 - in lepromatous
Erythema nodosum
Sudden eruption of multiple painful nodules
Diagnosis
Skin biopsy
Acid fast test
Pcr
Diagnosis of leprosy
Skin biopsy
Acid fast test
Pct
Treatment of leprosy
Single lesion - rifampicin
Pauci- rifampicin plus dapsone 6months
Multi- rifampicin plus dapsone plus clofazimine 12months
