LETS GOOOO

Question 1

What is Bioterrorism defined as?

Answer 1

Intentional use of bacteria, viruses, fungi, or toxins to injure people, animals, or crops to cause civil and economic unrest

Question 2

What is Biological warfare defined as?

Answer 2

Deliberate use of bacteria, viruses, fungi, or toxins to injure people, animals, or crops to gain a military or political advantage

Question 3

What are the different biosafety levels?

Answer 3

BSL1 (Don’t usually cause disease)
BSL2 (Not readily transmitted)
BSL3 (Serious disease; Respiratory)
BSL4 (Serious disease; No treatment)

Question 4

What are the three categories of biological agents?

Answer 4

Cat A (Greatest impact)
Cat B
Cat C (Lesser impact)

Question 5

What are some Cat A agents?

Answer 5

Bacillus anthracis
Francisella tularensis
Yersinia pestis

Question 6

What are some Cat B agents?

Answer 6

Brucella spp.
Burkholderia mallei
Salmonella
Escherichia coli O157:H7

Question 7

What are the Category C agents?

Answer 7

Mycobacterium tuberculosis
Hantavirus
Yellow fever virus
Hemorrhagic fever (Tickborne)

Question 8

What was established in 1999 by the CDC, APHL, FBI, and USAMRIID?

Answer 8

Laboratory Response Network (LRN)

Question 9

What are the different types of labs in the LRN?

Answer 9

Sentinel Labs (BSL2, Rule out/refer)
Reference Labs (Confirmatory)
National Labs (CDC, USAMRIID, Naval Med Research Center)

Question 10

What happened in 1984 in restaurants?

Answer 10

Liquid based Salmonella attack

Question 11

What prohibits the use of biological agents during war that has been signed by many nations?

Answer 11

Geneva Protocol

Question 12

What was the purpose of the Public Health Security and Bioterrorism Preparedness and Response Act of 2002?

Answer 12

Limit the possession, use and transfer of select agents and toxins

Question 13

What makes an ideal agent?

Answer 13

High attack and fatality
Little immunity
Easy to spread
Short time period between exposure and death

Question 14

What accounts for 95% of cases, causes a black eschar to form on the skin, and is the moat common form of the disease?

Answer 14

Cutaneous anthrax

Question 15

What is the most deadly type of anthrax?

Answer 15

Inhalation anthrax

Question 16

What is the specimen of choice for anthrax?

Answer 16

Vesicular fluid from lesions

Question 17

How do we microscopically identify anthrax?

Answer 17

Large, square ended, boxcar like gram positive bacilli
Aerobic
Catalase positive
Nonmotile

Question 18

What disease was first recorded in Egypt in 541 AD and lasted almost 200 years?

Answer 18

Yersina pestis (Black death)

Question 19

What are the forms of the plague?

Answer 19

Bubonic plague (Most common)
Septicemic plague
Pneumonic plague

Question 20

What is the specimen of choice for Yersinia pestis?

Answer 20

Blood cultures
Safety Pin appearance

Question 21

What is a zoonotic disease that also goes by the name of rabbit or deerfly fever and can infect with just 10 organisms?

Answer 21

Francisella tularensis

Question 22

What does F. tularensis most commonly present as?

Answer 22

Ulcerograndular tularemia

Question 23

What media does F. tularensis grow on?

Answer 23

Chocolate
MTM
Buffered Charcoal Yeast Extract (BYCE) agar

Question 24

What is a small, gram negative, pleomorphic, aerobic coccobacilli that requires BSL3 containment?

Answer 24

Brucella spp.
B. melitensis
B. suis
B. abortus

Question 25

What is a gram negative coccobacilli/bacilli with poor growth at 24 hours that is resistant to polymyxin B and colistin disks?

Answer 25

Burkholderia spp. B. mallei

Question 26

What does Variola virus cause?

Answer 26

Smallpox

Question 27

What guideline defines the detection and identification of smallpox based on the patient's signs and symptoms?

Answer 27

CDC's acute generalized vesicular or pustular rash protocol

Question 28

What is considered presumptive until confirmed by the CDC?

Answer 28

Positive variola virus