LEUCEMIA LINFOCÍTICA CRÓNICA Flashcards

1
Q

FACTORES DE RIESGO ASOCIADOS?

A

Hombres de edad avanzada
EXPOCISIÓN A :
Benzenos
Solventes

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2
Q

SIGNOS Y SÍNTOMAS

A

PERDIDA DE PESO
ANEMIA
TROMBOCITOPENIA

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3
Q

TRIADA CLÁSICA DE LLC

A

LINFADENOPATÍA

HEPATOESPLENOMEGALIA

LINFOCITOSIS ( +5,000 X 3 MESES )

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4
Q

MEJOR PRUEBA DIAGNÓSTICA?

A

Aspirado de medula ósea encontrando +- 30% de infiltrado de linfocitos maduros

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5
Q

delecion mas comun del cromosoma?

A

13Q

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6
Q

con base a la escala RAI Y BINET Cuando se debe dar TX ?

A

RAI 3 Y BINET C

FLUDARABINA + CICLOFOSFAMIDA + RITUXIMAB

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7
Q

CUANDO SE DEBE DAR ESQUEMA FC Y CUAL ES?

A

Si salen CD20 ( - )

FLUDARABINA + CICLOFOSFAMIDA

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8
Q

CUANDO SE DEBE DAR EL ESQUEMA FCR Y CUAL ES?

A

Si salen CD20 ( + )

FLUDARABINA + CICLOFOSFAMIDA + RITUXIMAB

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9
Q

Mecanismo de acción del RITUXIMAB

A

Inhibidor de CD20

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10
Q

Cuando se agrega CLORAMBUCILO?

A

EN PACIENTES DE 60 AÑOS O MÁS

O EXISTE ALGUN COMORBIDO

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