leucocyte disorders

Question 1

Differentials for quantitative alterations:
* Monocytosis:

Answer 1

Chronic inflammation; stress leucogram

Question 2

Differentials for quantitative alterations:
* Lymphocytosis:

Answer 2

Adrenalin release in cats. If severe or atypical morphology: likely neoplastic (leukaemia)

Question 3

Differentials for quantitative alterations:
* Lymphopenia:

Answer 3

Acute inflammation (e.g. acute viral infection); ‘Stress leucogram’ (due to endogenous or exogenous steroids).

Question 4

Differentials for quantitative alterations:
* neutrophilic:

Answer 4

usually due to inflammation. Many causes: infection, tissue damage, necrosis. It can also be due to chronic stress response (or steroid administration).

Question 5

Differentials for quantitative alterations:
* neutropenia:

Answer 5

overwhelming tissue demand, reduced bone marrow production or increased destruction (immune-mediated). It may be transient so always recheck full blood count!

Question 6

Differentials for quantitative alterations:
* left shift:

Answer 6

acute inflammation

Question 7

Differentials for quantitative alterations:
* Eosinophilia:

Answer 7

worm parasitism, allergy—type 1 hypersensitivity

Question 8

Differentials for quantitative alterations:
* Basophilia:

Answer 8

usually follows eosinophilia and is due to similar causes