Leukocytes--white blood cells Flashcards Preview

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Flashcards in Leukocytes--white blood cells Deck (30)
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1
Q

what is the shape of the leukocytes?

A

spherical shape

2
Q

what are the functions of the leukocytes?

A
  1. protection from foreign microorganism

2. remove dead cells and debris

3
Q

what are the movements of the leukocytes?

A
  1. movement in blood

2. movement in ameboid in tissues

4
Q

why do we want leukocytes to leave out of your blood vessels?

A

to move through tissue

5
Q

what are the two classifications of the leukocytes?

A
  1. granulocytes

2. agranulocytes

6
Q

what is meant by granulocytes?

A

they have granules

7
Q

what are the granulocytes of the leukocytes?

A
  1. neutrophils (aka: PMN’s)
  2. basophils
  3. eosinophils
8
Q

what are the agranulocytes of the leukocytes?

A
  1. lymphocytes

2. monocytes

9
Q

what are meant by agranulocyte?

A

has NO granules

10
Q

granules are collection of what?

A

collection of enzymes

11
Q

which granule is most common in the leukocytes?

A

neutrophils

12
Q

what is the % of neutrophils in leukocytes?

A

60-70%

13
Q

neutrophils have a lining in the inner surface of the nuclear envelope. what is the name of this lining?

A

heterochromatin

14
Q

the nucleus in neutrophils has how many lobes?

A

2-5 lobes (usually 3 lobes)

15
Q

neutrophils have few of what organelle?

A

few mitochondria

16
Q

what are the specific granules neutrophils have?

A
  1. alkaline phosphates
  2. collagenase
  3. lactoferrin
  4. 2/3’s of cells lysozyme
17
Q

these are known as what?

A

collection of enzymes

18
Q

what are the deep reddish purple granules in neutrophils?

A

azurophilic granules

19
Q

what are azurophilic granules?

A

primary lysosome

20
Q

why do neutrophils use these different kinds of enzymes?

A

to break down and kill foreign substances or to clean up debris

21
Q

neutrophils are known to be the first what?

A

first to arrive at injury or inflammation; first sign of defense

22
Q

what is the life of neutrophils?

A

short half-life, 1 to 4 days

23
Q

where are neutrophils formed?

A

medullary formation

24
Q

what are the 4 compartments in the neutrophils?

A
  1. medullary storage
  2. circulating “patrolling”
  3. marginating (temporary excluded from the circulatory)
  4. connective tissue
25
Q

summary of neutrophils

A
formed in the medullary 
....stays in the bone
....circulates in the blood
....can get out of the blood and
....wonder around in the connective tissues
26
Q

what do you call the process in which PMN’s enter circulation from connective tissue?

A

Diapedesis

27
Q

what is the function of the diapedesis?

A

phagocytosis (engulfing and then digesting of solid waste or foreign material by cell)

28
Q

presence of what, is in response to stimuli and NOT created by increase production?

A

presence of PMN’s

29
Q

define stimuli

A

muscle activity, epinephrine release, bacterial infection

30
Q

what should you remember about Neutrophils?

A

they are the FIRST sign of defense, the first cell that shows up at the sight of infection or inflammation