Leukopoiesis and Function Flashcards
(14 cards)
Where do WBCs originate from?
Pluripotent Stem Cells
What do PSCs give rise to?
Myeloid and Lymphoid stem cells
WBCs
What are the two WBC pools?
Circulating Pool: Bloodstream
Marginating Pool: Vessel Endothelium
What are the ways we can differentiate WBCs?
Cell Size
Nucleus : Cytoplasm Ratio
Chromatin Pattern
Cytoplasmic Quality
What cell stage is the largest?
Promyelocyte
Nonspecific Granules
What is the first stage with specific granules?
Myelocyte
What is responsible for Blood Filtration, Fluid Balance, Antibody Generation, and Lymphopoiesis?
The Lymphatic System
What are the secondary locations Lymphocytes can be produced?
Spleen
Lymph Nodes
GI Tract
Tonsils
Which type of immunity does a T cell and a B cell have?
T: Cell Mediated
B: Humoral
What plays a role in resisting bacteria, viruses, and fungi?
Natural Killer (NK) Cells
Which stage has a N:C ratio of 1-1 and a kidney bean nucleus?
Metamyelocyte
Which stage has 2-5 lobes of nucleus and has a pale lilac chromatin?
Segmented Neutrophil
Which stage has a N:C ratio of 6-1, is round oval with 2-5 nucleoli, and a basophilic cytoplasm?
Blast
Which stage has nuclei that take different shapes such as brainy convolutions or S shapes and has a gray-blue cytoplasm?
Monocyte
