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Flashcards in Lewis System Deck (11):
1

Genes: LeLe and Sese Le antigens:____

Le antigens: Le^a and Le^b

2

Genes LeLe and sese Le antigens:___

Le^a

3

Genes lele and SeSe Le antigens:___

none (H antigens)

4

the secretor gene( Se FUTZ gene) codes for an enzyme that adds fucos to the ____

terminal Galactose

5

The Le gene (FUT3 gene) codes for an enzyme that codes for an enzyme that adds fucose to the ____

subterminal GLcNAc

6

newborns are born with Le(a__b__) on there RBC's then transition for Le(a__b__)

Le(a-b-)
Le(a+b+)

7

what class of immunoglobulin are Lewis antigens?

IgM

8

enzymes that change the Ag expression or Ab binding are called

proteolytic enzymes

9

true or false
Lewis antibodies are naturally occuring

true

10

which Lewis antibody has variants?

anti-Le^b

11

why does the Lewis system not really matter for HDFN?

-Lewis antibodies are primarily IgM (cant cross the placenta)
-baby red cells are Le(a-b-)