Life at a Cellular Level 4 Flashcards

(32 cards)

1
Q

What does water do/

A
  • Bathes our cells
  • Dissolves and transports compounds
  • Allows compounds to move within an between cells
  • Participates in chemical reactions
  • Dissipates heat
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2
Q

Describe the structure of water.

A
  • Polar molecule

- Electrons of covalent bond attracted to O

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3
Q

What does the polarity of water allow?

A

Hydrogen bonding

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4
Q

Where can hydrogen bonds occur?

A

Between any electronegative atom and a H atom that is electropositive

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5
Q

When are hydrogen bonds strongest?

A

When the 3 atoms involved lie in a straight line

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6
Q

What are examples of hydrophilic substances that can dissolve in water?

A
  • Sugars
  • Alcohols
  • Aldehydes
  • Ketones
  • Compounds with N-H groups
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7
Q

What happens when hydrophilic substances dissolve in water?

A

The water-water H bonding and solvent-solvent H bonding is replaced with more energetically favourable solute-water H bonding

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8
Q

How do O2 and CO2 dissolve if they have no polarity?

A
  • The atoms lie in a straight line so the ends of the molecule are the same so a partial charge does not happen
  • this makes O2 and CO2 relatively poorly water soluble
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9
Q

What happens to ionic compounds in water?

A

The water forms screens around each ion keeping the compound in solution once it has dissolved.

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10
Q

How do hydrophobic molecules arrange themselves in water?

A
  • To minimise disruption of hydrogen bonding among surrounding water molecules
  • This proves the most energetically favourable arrangement of the molecules
  • This is the hydrophobic effecys
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11
Q

Describe lipids in water

A
  • Lipid portions at the edge of the cluster force the ordering of water
  • Fewer H2O molecules are ordered, and entropy is increased
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12
Q

What happens to phospholipids in water?

A

They minimise the disruption of water-water H-bonds by forming micelles or bilayers

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13
Q

What happens if you put lots of phospholipids in water?

A

They can form liposomes

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14
Q

What happens to proteins in water?

A
  • Hydrophobic regions of the protein chain on the inside and hydrophilic regions on the outside
  • This allows them to be water soluble
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15
Q

How are hydrophobic lipids transported in the blood?

A

-Transported as chlomicrons

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16
Q

How is the equilibrium of water described?

A

Keq= [H][OH]
———-
[H2O]

17
Q

What is the ion product of water equal to?

A

1 × 10^-14 (mol/L)2

18
Q

What is true in pure water?

A

[H]=[OH]=1 × 10^-7(mol/L)

19
Q

What is a strong acid?

A

An acid which fully dissociates in water like HCl

20
Q

What is a weak acid?

A

An acid which partially dissociates in water

21
Q

How is optimal pH maintained?

A

Using buffer systems within cells and organisms

22
Q

What are buffers?

A

Solutions of weak acids

23
Q

What is a proton donor?

24
Q

What is a proton acceptor?

25
What do a proton donor and proton acceptor make up?
Conjugate acid-base pair
26
What is the Henderson-Hasselbalch equation?
-A way of relating the acid dissociation equation to the buffering ability of a weak acid/conjugate base - pH=pKa + log [A] ---- [HA]
27
What buffer is important in our cells?
Phosphate buffer
28
What buffer is important in our plasma?
Bicarbonate buffer
29
What can the Henderson-Hasslebalch equation be used to calculate?
How th pH of a physiological solution responds to changes in either the conjugate acid or base
30
What metabolic conditions are buffers particularly important for?
- Respiratory acidosis and alkalosis | - Metabolic acidosis and alkalosis
31
Without a buffer what would cause significant decreases in blood pH?
- Lactic acid | - Ketone bodies
32
What pH should blood be maintained at?
7.4