Life at a Cellular Level Flashcards

1
Q

In eukaryotic cells, what is the role of the nucleus?

A

Contains DNA
Site of ribosomal RNA synthesis
‘Control centre’ of cell

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2
Q

In eukaryotic cells, what is the role of the mitochondria?

A

Site of ATP production

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3
Q

In eukaryotic cells, what is the role of lysosomes?

A

Used to separate enzymes from the rest of the cell to prevent the cell digesting itself

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4
Q

In eukaryotic cells, what is the role of the ER?

A

Rough ER is site of protein synthesis

Smooth ER allows breakdown of substances

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5
Q

In eukaryotic cells, what is the role of the Golgi Apparatus?

A

Modification and Packaging of proteins into lysosomes

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6
Q

In eukaryotic cells, what is the role of the nucleolus?

A

Site of ribosomal RN synthesis and ribosomal activity

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7
Q

What are the three types of cytoskeleton filament?

A
  1. Microfilaments
  2. Microtubules
  3. Intermediate Filaments
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8
Q

What is the role of microfilaments?

A

Made up of Actin

Involved in movement

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9
Q

What is the role of microtubules?

A

Made up of Tubulin
Holds contents of cell in place
Make up cilia and flagella

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10
Q

What is the role of intermediate filaments?

A

Holds contents of cell in place

Linked to mytosis

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11
Q

What is the role of peroxisomes?

A

Involved in the metabolism of very long fatty acid chains

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12
Q

What are the 5 chemical reactions of living things?

A
  1. Redox reactions
  2. Making and breaking C-C bonds
  3. Internal rearrangements
  4. Hydrolysis and Condensation
  5. Group tranfers
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13
Q

What two laws govern energy changes?

A
  1. Energy can neither be created or destroyed but only transform from one form to another (Total energy of closed system is constant)
  2. All energy transformations lead to increased entropy/ disorder.
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14
Q

What is Gibbs Free Energy equation?

A
G= H- TS
G= Free Energy
H= Enthalpy
T= Absolute temperature
S= Entropy
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15
Q

Using Gibbs Free Energy equation, how could you know if a reaction will occur?

A

A reaction will be spontaneous if delta G< 0

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16
Q

What process allows thermodynamically unfavourable reaction to occur?

A

Energy coupling

17
Q

What is meant by the term metabolism?

A

The chemical process in living organism by which food is used for tissue growth

18
Q

What is meant by the term anabolism?

A

Reactions in which larger molecules are created from smaller ones
These reactions require energy

19
Q

What is meant by the term catabolism?

A

Reactions in which larger molecules are broken down into smaller ones
These reactions release energy

20
Q

How is water polar?

A

More electronegative oxygen attracts a greater share of the bonding electrons, giving it a slightly negative charge with respect to the hydrogens it is attached to.

21
Q

What is meant by the term ‘amphipathic’?

A

A molecule containing a hydrophilic and hydrophobic group (e.g. phospholipids)

22
Q

What structures do phospholipids form in water?

A

Micelles/ Bilayers

23
Q

What is the numerical value for the Kw of water?

24
Q

How do you calculate pH of a substance?

A

pH= -log[H]

25
What defines the strength of an acid?
Its tendency to lose a proton
26
What type of acid is required to create a buffer solution
A weak acid
27
What buffer system acts in the cells of the body?
Phosphate buffer system | H2PO4 H+ + HPO4-
28
What buffer system acts in the blood plasma?
Carbonate buffer system | H2CO3 H+ + HCO3-
29
What is the Henderson-Hasselbalch equation?
pH= pKa + log [A-]/ [HA]
30
What are tight junctions?
Junctions creating a physical barrier to diffusion across layers of cells
31
What are desmosomes?
Junctions linking keratin filaments from two different cells
32
What are adherens?
Junctions linking actin filaments from two different cells
33
What are gap junctions?
Junctions forming channels to link the cytoplasm of two different cells. Allow cell to cell communication.
34
What type of amino acids are all proteins made from?
L amino acids