Lipid Flashcards
(18 cards)
HDL
Greater than 40 in males
Greater than 50 in females
You can subtract a risk factor of over 60
Recommendation for screening age 20 and older
Fasting lipoprotein with TC, LDL, HDL, TG and every 5 years
If younger can screen if family history or other risk factors
Secondary causes of lipid disorder
Alcohol
Drugs-OCP, androgens, steroids, thiazides, BB; glucosamine
Obesity
Improper diet
DM
Hypothyroid
Cushings or Addison
Nephrotic syndrome
CKD
Acute stress-MI, sepsis, burns, pancreatitis
Pregnancy
Treat underlying cause then recheck
Lipoprotein A
Levels greater than 30 independent risk factor for CHD
More atherogenic than LDL
Increased in renal disease, post menopausal, family history of CHD
C reactive protein
Inflammatory marker
Independent risk factor for CHE
Not correlated with LDL
Drugs for HLD
Statins- drug of choice for elevated LDL ***
Niacin- lowers TG and LDL, raises HDL, does not reduce MM, do not use with statin
Fibrates- LDL effects variable, lowers TG, raise HDL, contradicted with statin use
Bile acid resins- Lowe LDL, may increase TG, HDL
Omega 3 fatty acid- lower TG and LDL, raises HDL
Mr smith is a 50 year old obese man with untreated HTN
He has a fasting BS of 220 you expect the lipid panel to show
Mildly elevated LDL, low HDL, high TG
Which of the following are benefits of statins
All of the above- plaque stabilization, resort function of vascular endothelial, may decrease prothrombotic and inflammatory state
The non HDL maximum for a patient is ____ points above the______ goal
30 points, LDL
Knowing the patients non HDL cholesterol number is important because it indicates
How may atherogenic particles are present in addition to the measure LDL
Therapeutic lifestyle changes are recommended for patients with an elevated cholesterol level patient education should include
High fiber diet
Low fat diet
A patient who complains of muscle pain after starting a staying should have the following labs done
CPK and TSH
The AHA cholesterol guidelines recommend the use of statin therapy in the diabetic population aged 40-75 based on the following
Having a DM diagnosis
The following elements are often associated with insulin resistance
Small dense LDL particles
High intensity statin
Atorva 40
Atorva 80
Rosuva 20
Rosuva 40
Mod intensity statin
Atorva 10, 20
Rosuva 5, 10
Simva 20,40
Prava 40,80
Lova 40, 80
Fluva 80, 40 BID
Pita 1-4 mg
Low intensity statin
Simva 10
Prava 10, 20
Fluva 20,40
Adjuncts
Zetia 10
Bile acid sequestrants
PCSK9 inhibitors
