Lipid management in PWD Flashcards
Age < 40 No ASCVD; no 10 year risk > 20%
No statins
Age < 40 with ASCVD risk > 20%
High dose statin/combo
Age 40 or more, no CVD but with > 20% risk ASCVD
moderate intensity statins
age 40+ with ASCVD and > 20% risk
high intensity; if LDL > 70 add ezetimibe or PCSKA inhibitor
ASCVD risks include:
LDL > 100, HTN, CKD, Albuminuria, Fam hx ASCVD
Age 20-39
If Type 2 > 10 years or Type 1 > 20 years, > 30 mg albuminurea-> Moderate intensity statins
Age 40-75 regardless of ASCVD risk
moderate intensity statins with goal decrease LDL by 30%
Age 75 or older
ASCVD risk not valid; continue present tx; if none- consider pros/cons
All agese with clinical ASCVD or 10 year risk > 20%
High intensity rx with goal LDL-C reduction 50%
TG modesly elevated (175-499)
Initiate or intensify statins add icospent ethyl2 g BID or fenofibrate
Severe TG elevations > 500 mg/dL
goal is prevent pancreatitis; initiate/intensify statins; add fibrate or omega 3 FA
Diet recs for elevated TG
Weight loss; limit carbs, avoid etoh; very low fat diet
Atorvistatin
Lipitor; 10-80 mg daily
Lipitor AE
myopathy: ** Don’t use if LFTs 3X UL normal
Each doubling of lipitor dose reduces LDL _____%
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