Lipid Synthesis Flashcards Preview

BMSC 230--Metabolism > Lipid Synthesis > Flashcards

Flashcards in Lipid Synthesis Deck (5)
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1
Q

What catalyses the sequential attachment of fatty acids to glycerol backbone?

A

Acyltransferase, through an ester bond

2
Q

What is the active form of a fatty acid?

A

A fatty acid attached to coenzyme A derivative (Acyl-CoA)

3
Q

How is the glycerol-3-phosphate backbone made?

A

By reducing DHAP to glycerol-3-phosphate using glycerol-3-phosphate dehydrogenase

4
Q

Which fatty acids are saturated and unsaturated in a phospholipid?

A

The first FA is usually saturated, while the middle one is usually unsaturated

5
Q

How is DAG activated?

A

By adding on CDP (cytidine diphosphate) to form CDP-diacylglycerol; it then reacts with an alcohol to form a phospholipid