LIPIDS

Question 1

These diverse compounds that make up
the lipid family are so grouped because
they are

Answer 1

insoluble in water

Question 2

They are also ____ in other organic
solvents such as ether, acetone, and other
lipids.

Answer 2

soluble

Question 3

serve a variety of important
functions in living organisms.
* They act as chemical messengers, serve as
valuable energy sources, provide
insulation, and are the main components
of membranes.

Answer 3

lipids

Question 4

Major lipid groups
include

Answer 4

fats

, phospholipids

, steroids,

and waxes

Question 5

The chemical term includes fats, oils,
and related compounds that are insoluble in
water and greasy to the touch.
* Some food lipids—butter, margarine, or
cooking oil—are easily recognized as fats.
* Other foods that appear to be
carbohydrates, such as bakery items or
potato chips, often contain significant
amounts of fat.

Answer 5

lipid

Question 6

Lipids are ____compounds
consisting of a carbon chain with
hydrogen and oxygen atoms attached.
Particular lipids may have other
radicals or groups of elements
attached.
* Fatty acids and their related
compounds are the lipids important in
human nutrition.

Answer 6

organic

Question 7

Lipids have something in common with
carbohydrates: the same chemical elements that
make up carbohydrates
the same chemical elements that make up
carbohydrates—

Answer 7

carbohydrates—carbon, hydrogen, and oxygen—also
make up fatty acids. However, carbohydrates and
lipids have two important structural differences:

Question 8

Lipids are more ____, with more carbon (C)
and hydrogen (H) atoms and fewer oxygen (O)
atoms.

Answer 8

complex

Question 9

The common structural units of lipids are fatty
acids, whereas the common structural units of
carbohydrates are .

Answer 9

simple sugars

Question 10

The saturation or unsaturation of a lipid governs its physical characteristics:

Answer 10

1. Saturated fats are hard
2. Less-saturated fats are soft
3. Unsaturated fats are liquid at room temperature

Question 11

Lipids composed mostly of saturated fatty acids are called saturated fats.
Although saturated fatty acids are usually found in animal foods, the most saturated
food fats are two oils from plants: (1) coconut oil, which is 88% saturated, and (2)
palm kernel oil, which is 80% saturated. All other saturated fats are of animal origin
as found in meat; butter; whole, reduced-fat, and low-fat milk; and other dairy
products.

Answer 11

Saturated

Question 12

Food lipids that have a high proportion of fatty acids with a pair of
hydrogen atoms missing, creating one double bond, are called monounsaturated fats.
These lipids are generally from plant sources. Canola oil (isolated from rapeseed) and
olive oil are primarily mono- unsaturated fats.

Answer 12

monosaturated

Question 13

When fatty acids have four or more spaces unfilled with
hydrogen atoms, creating two or more double bonds, they are
polyunsaturated fats. Many of these fats are from plant sources and include
commonly used cooking oils such as corn oil and safflower oil.
Polyunsaturated fatty acids with two or more double bonds are also classified
according to the position in the carbon chain where the first double bond
appears. These are referred to as essential fatty acids because the body cannot
synthesize an n-3 or n-6 fatty acid. The n-3 fatty acids found in fatty fish have a
role in cardiovascular health.

Answer 13

Polyunsaturated:

Question 14

Two different fatty acids—linoleic acid (an n-6 fatty
acid) and α-linolenic acid (an n-3 fatty acid) are
essential fatty acids for humans. Arachidonic acid,
another fatty acid important in human nutrition, can be
made from linoleic acid. Two n-3 fatty acids associated
with cardiovascular health—(1) eicosapentanoic acid
(EPA) and (2) docosahexaenoic acid (DHA)—can be
made from α-linolenic acid but these conversion rates
are extremely slow,13,14 and influenced by age, sex,
genetics, and overall dietary intake. Therefore,
individuals need to obtain these acids from regular
servings of fish.

Answer 14

Essential Fatty Acids

Question 16

The essential fatty acids strengthen cell membranes and prevent a harmful
increase in skin permeability. Essential fatty acid deficiency causes breakdown in skin tissue,
with characteristic eczema and skin lesions. Essential fatty acid deficiency seldom occurs
with the exception of a patient receiving a parenteral nutrition formula that does not
include the essential fatty acids.

Answer 16

Skin integrity:

Question 17

Polyunsaturated fatty acids can reduce blood lipid levels,
particularly if they are replacing saturated fat in the diet.

Answer 17

Regulation of lipid metabolism:

Question 18

Normal growth requires an adequate supply of the essential fatty acids, and growth
is impaired in essential fatty acid deficiency; α-linolenic acid is especially important for the
development of brain tissue before and after birth.

Answer 18

Growth

Question 19

The essential fatty acids regulate the production of enzymes needed for
synthesis of nonessential fatty acids.

Answer 19

Gene expression

Question 20

Persons with essential fatty acid deficiency have an increased rate of
infection.

Answer 20

Immune Function

Question 21

EPA and DHA prevent unwanted aggregation of blood platelets
that blocks the flow of blood in major arteries, causing heart attack or stroke.

Answer 21

Aggregation of blood platelets:

Question 22

Essential fatty acids are metabolic precursors of a group of
physiologically and pharmacologically active compounds known as eicosanoids

Answer 22

• Synthesis of hormonelike agents:

Question 23

Arachidonic acid and DHA play a critical role in
the brain and neural development of infants;
both are found in breast milk in liberal
amounts. Commercial infant formula sold in the
United States is fortified with arachidonic acid
and DHA to the levels found in human milk.
Based on the important role of DHA in both
prenatal and postnatal development, some
nutrition experts have proposed that both
pregnant and lactating women of DHA from
fish or supplements during pregnancy, the DHA
content of breast milk, and infant health
outcomes such as visual acuity and cognitive
development.

Answer 23

Special Needs of Infants

Question 24

The best sources of the two essential fatty acids
are vegetable oils. Corn oil, safflower oil, soybean
oil, cottonseed oil, sun- flower oil, and peanut oil

are rich in linoleic acid (an n-6 acid), and α-
linolenic acid (an n-3 acid) is found in flaxseed,

soybean oil, and rapeseed oil (canola oil).

Answer 24

Food Sources of Essential Fatty Acids

Question 25

which have received
increasing attention in the popular press
as an alternative to eating fish, should be
used only with the supervision of a health
care professional. Because EPA and DHA
can excessively prolong bleeding time,
persons taking anticoagulants including
warfarin and aspirin should use such
supplements with caution.

Answer 25

Use of Fish Oil Supplements

Question 26

The body stores fatty acids in the form of
triglycerides made from three fatty acids attached
to a glycerol base. When glycerol is combined with
one fatty acid, it is called a monoglyceride; with two
fatty acids, it is a diglyceride; and with three fatty
acids it is termed a triglyceride. Glycerides are found
in food and also formed in the body. Most natural
lipids from animal or plant sources are triglycerides.
Triglycerides serve multiple functions throughout
the body. They appear in body cells as oily droplets
and circulate in the water-based blood plasma
encased in a covering of water-soluble protein.
These lipid-protein molecules are called lipoproteins.

Answer 26

Structure of Triglycerides

Question 27

To meet the demand for solid fats for use as table fats or food ingredients the process of
________ was developed.

Answer 27

hydrogenation

Question 28

have been implicated in the development of coronary artery disease. In addition, they
elevate the risk of type 2 diabetes and disrupt essential fatty acid functions in cells

Answer 28

Trans fatty acids have

Question 29

Although _____ is not a fat or a triglyceride, it is often discussed in connection with dietary
lipids. Cholesterol belongs to a family of substances called steroids and travels in the blood
attached to long-chain fatty acids. People some- times confuse cholesterol with saturated fat
because both substances are believed to promote atherosclerosis.

Answer 29

cholesterol

Question 30

is found in animal foods but not plant foods. Egg yolk; meat; whole, reduced-fat, and
low-fat milk; cheese; and organ meats supply cholesterol. Animal fats (but not plant fats) are rich
sources.

Answer 30

cholesterol

Question 31

is required for normal body function and synthesized in the liver. If a
person obtained no cholesterol whatso- ever from food, the body would still have an
adequate supply. Cholesterol has broad roles as follows:

• Precursor to steroid hormones: A cholesterol compound in the skin,
  7-dehydrocholesterol, is converted to vitamin D when the ultraviolet rays of the sun
  pass into the skin; cholesterol is also a precursor of estrogen and testosterone.
  *Formation of bile acids: Cholesterol is used to form bile acids, which emulsify fats and
  facilitate their digestion; bile acids serve as carriers in fat absorption.
  *Component of brain and nerve tissue: The brain and nerves include cholesterol in their
  structure.
  *Component of cell membranes: Cell membranes contain cholesterol.

Answer 31

Cholesterol

Question 32

The liver is the body clearinghouse for fatty acids and cholesterol, whether supplied in
food or produced in body tissues. When received by the liver, fatty acids and
cholesterol are packaged into lipoproteins and released into the circulation for
transport to cells.

Answer 32

Lipoproteins

Question 33

Lipids are insoluble in water, which poses a problem when they need to be carried in a
water-based circulatory system. The body solves this problem by producing
lipoproteins, a complex of lipids and lipid like substances surrounded by water-soluble
protein.
* Special compounds called phospholipids are important in the structure of lipoproteins.
Phospholipids are molecules in which one of the three fatty acids attached to a glycerol
base is replaced with a phosphate (PO4−3) group that is water soluble and assists in the
transport of lipoproteins.
* Phospholipids in cell membranes help lipid molecules move from the circulatory system
into the cell.
* Lipoproteins contain fatty acids, triglycerides, cholesterol, phospholipids, and traces of
fat-soluble vitamins and steroid hormones.

Answer 33

Lipid Transport

Question 34

are classified according to their density, as determined by their
relative content of lipid and protein. The more protein present, the greater
the density. The amount of each lipoprotein in the blood is influenced by the
time since the last meal and the quantity and type of fat that a person
consumes on a regular basis. The five lipoprotein classes are as follows:

Answer 34

Lipoproteins

Question 35

These relatively large particles are formed in the intestinal wall after a meal and carry the
digested and absorbed fat to the liver for conversion to other lipoproteins.

Answer 35

Chylomicrons:

Question 36

The VLDLs are formed in the liver during the fasting interval
between meals. When there is no food in the digestive tract and chylomicrons are not entering the
circulatory system, VLDLs transport endogenous triglycerides from the liver to tissue cells.

Answer 36

Very low-density lipoproteins (VLDLs):

Question 37

IDLs are formed from VLDLs and continue the delivery of
endogenous triglycerides to the cells.

Answer 37

Intermediate-density lipoproteins (IDLs):

Question 38

LDLs are formed from VLDLs and IDLs and carry mainly cholesterol, as
most of the triglyceride has already been moved into cells.

Answer 38

Low-density lipoproteins (LDLs):

Question 39

HDLs return cholesterol from the cells to the liver for breakdown and
excretion.

Answer 39

High-density lipoproteins (HDLs):

Question 40

short chain faty acids contain

Answer 40

4 to 6 carbon atoms

Question 41

medium-chain fatty acids have

Answer 41

8, 10, or 12 carbon atoms

Question 42

long-chain fatty acids haves

Answer 42

14, 16, 18, or more carbon atoms

Question 43

Highly saturated fat (solid at room temp)

Answer 43

stick margarine
butter
beef fat

Question 44

less-saturated fat (very soft at room temp)

Answer 44

tub margarine
squeeze margarine

Question 45

unsaturated fat (lipid at room temp.)

Answer 45

salad oil