Lipids Flashcards

(43 cards)

0
Q

Primary source of fuel

A

Lipids

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1
Q

Commonly referred to as fats

A

Lipids

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2
Q

Conjugated lipids

A

Phospholipids

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3
Q

Most abundant lipids are derived from where?

A

Phosphatidic acid

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4
Q

Formed by the conjugation of two fatty acids and a phosphorylated glycerol

A

Phospholipids

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5
Q

Only phospholipid not derived from glycerol

A

Sphingomyelin

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6
Q

Sphingomyelin is derived from an amino alcohol called __________

A

Sphingosine

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7
Q

Sphingomyelin accumulates in the liver and spleen of patients suffering from what?

A

Niemann-Pick disease

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8
Q

Unsaturated steroid alcohol containing four rings and has a single C-H side chain tail similar to fatty acids

A

Cholesterol

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9
Q

True or False: Cholesterol serves as a source of fuel

A

False

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10
Q

Transport and excretion of cholesterol is promoted by what hormone?

A

Estrogen

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11
Q

Precursor of five major classes of steroids

A

Cholesterol

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12
Q

Cholesterol bound to fatty acid (hydrophobic form)

A

Cholesterol ester

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13
Q

Catalyzes the eterification of cholesterol by promoting the transfer of fatty acids from lecithin to cholesterol

A

Lecithin-Cholesterol Acyl Transferase (LCAT)

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14
Q

Activator of LCAT

A

Apo A-1

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15
Q

Polar nonesterified form of alcohol

A

Free cholesterol

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16
Q

Linear chains of carbon-hydrogen bonds that terminate with a carboxyl group

A

Fatty acids

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17
Q

Provide substance for conversion to glucose (gluconeogenesis)

18
Q

Enzyme that hydrolyzes TAG in lipoproteins and release of fatty acid and glycerol

A

Lipoprotein lipase

19
Q

Enzyme that hydrolyzes TAG and phospholipids from HDL

A

Hepatic lipase

20
Q

Enzyme that hydrolyzes lipids on VLDL and IDL

A

Hepatic lipase

21
Q

Catalyzes the esterification of cholesterol from HDL

22
Q

Enables HDL to accumulate cholesterol as cholesterol ester

23
Q

Hydrolyzes phospholipids and TAG in HDL

A

Endothelial lipase

24
Its main purpose is to transport TAG and cholesterol to sites of energy storage and utilization
Lipoproteins
25
Largest and least dense of the lipoprotein particles
Chylomicrons
26
Where are chylomicrons produced?
Intestine
27
Transports exogenous/dietary TAG to liver, muscles and fat depot
Chylomicrons
28
Which organ secretes VLDL?
Liver
29
Transports expgenous TAG from liver to muscle, fat depots and peripheral tissues
VLDL
30
Smallest lipoprotein and least dense
HDL
31
Alpha lipoprotein
HDL
32
Pre-beta lipoprotein
VLDL
33
Beta lipoprotein
LDL
34
Major end product resulting from the catabolism of VLDL
LDL
35
Most cholesterol-rich lipoprotein
LDL
36
Product of VLDL catabolism
Intermediate density lipoprotein (IDL)
37
Electrophoretic pattern of lipoproteins
HDL, VLDL, LDL, Chylomicrons
38
Subclass of LDL
IDL
39
“Sinking pre-B lipoprotein”
Lipoprotein a
40
Abnormal lpp found in obstructive jaundice and LCAT deficiency
Lipoprotein X
41
"Abnormally migrating B-VLDL"
B-VLDL/floating B-lpp
42
Reference mtd for the quantitation of lpp
Ultracentrifugation