Lipids Flashcards
(43 cards)
Primary source of fuel
Lipids
Commonly referred to as fats
Lipids
Conjugated lipids
Phospholipids
Most abundant lipids are derived from where?
Phosphatidic acid
Formed by the conjugation of two fatty acids and a phosphorylated glycerol
Phospholipids
Only phospholipid not derived from glycerol
Sphingomyelin
Sphingomyelin is derived from an amino alcohol called __________
Sphingosine
Sphingomyelin accumulates in the liver and spleen of patients suffering from what?
Niemann-Pick disease
Unsaturated steroid alcohol containing four rings and has a single C-H side chain tail similar to fatty acids
Cholesterol
True or False: Cholesterol serves as a source of fuel
False
Transport and excretion of cholesterol is promoted by what hormone?
Estrogen
Precursor of five major classes of steroids
Cholesterol
Cholesterol bound to fatty acid (hydrophobic form)
Cholesterol ester
Catalyzes the eterification of cholesterol by promoting the transfer of fatty acids from lecithin to cholesterol
Lecithin-Cholesterol Acyl Transferase (LCAT)
Activator of LCAT
Apo A-1
Polar nonesterified form of alcohol
Free cholesterol
Linear chains of carbon-hydrogen bonds that terminate with a carboxyl group
Fatty acids
Provide substance for conversion to glucose (gluconeogenesis)
Fatty acids
Enzyme that hydrolyzes TAG in lipoproteins and release of fatty acid and glycerol
Lipoprotein lipase
Enzyme that hydrolyzes TAG and phospholipids from HDL
Hepatic lipase
Enzyme that hydrolyzes lipids on VLDL and IDL
Hepatic lipase
Catalyzes the esterification of cholesterol from HDL
LCAT
Enables HDL to accumulate cholesterol as cholesterol ester
LCAT
Hydrolyzes phospholipids and TAG in HDL
Endothelial lipase