Lipids - Nutrition Flashcards

(33 cards)

1
Q

categories of fatty acids

A
  1. saturated
  2. monounsaturated (MUFA)
  3. polyunsaturated (PUFA)
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2
Q

where is the caloric content of macronutrient lipids mainly fount

A

the fatty acids -> acetyl CoA and generate ATP

9 kcal/g

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3
Q

different chain lengths of FA, what is the significance?

A

Long 14+ carbons
Medium 6-12 C
Short 2-4

absorbed in intestine differently

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4
Q

what kinds of fats are found in what plants (generally speaking)?

A

PUFAs - plants grown in cooler areas
ie soybeans

tropical plants have higher temps of saturated fats w/o having fluidity problems

olive oil, avocados, peanuts, pecans, almonds - monounsaturated fatty acids MUFAs

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5
Q

what fats are found in amimals?

A

more variability;
warm blooded - saturated fats (beef & pork)
cold water fish - polyunsat FA (esp Omega-3)

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6
Q

what are fats?

A

triglycerides

dont have phosphate in them

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7
Q

the importance of trans double bond vs cis?

A

trans bonds dont put a kink in the chain
so act more like saturated FA

some in meat and dairy due to bacterial fermentation

are hydrogenated to form margarine

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8
Q

whats the prob w trans FA?

A

well, sat and trans unsat fatty acids raise LDL levels

trans unsat FA also lower HDL

so margarine can be worse for you than butter

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9
Q

Linoleic acid

A

18:2 (n-6)

essential

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10
Q

alpha-linolenic acid

A

18:3 (n-3)

essential

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11
Q

arachidonic acid

A

20:4 (n-6)

derived from linoleic acid

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12
Q

why are essential fa important?

A

bc they are made into prostaglandins and leukotrienes

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13
Q

most of the EFA’s in the brain are…

A

linolenic (n-3)

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14
Q

essential fa deficiency symptoms;

A

prominent; scaly skin (n-6 more effective for fixing)
infertility (male and female)
reduced growth rates
increased RBC fragility
etc
(rest can be fixed w either n-3 or n-6 supp)

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15
Q

triene/tetraene ratio

A

EFA deficiency -> use oleat to make 20:3 n-9 a Triene

Tetraene (20:4) - eicosanoid form from n-6 and n-3

> 0.2 = EFA deficiency

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16
Q

triene/tetraene ratio criterion;

A
  1. geriatric, poor diet, esp w peripheral vasc disease
  2. fat malabsorption
  3. prolonged parenteral alimentation w formula deficient in EFAs
  4. burn pts
17
Q

are EFA’s PUFAs or MUFA’s?

A

PUFAs

note; not all PUFA are essential

18
Q

DHA (docosahexaenoic acid)

A

imp constituent of breastmilk

LCFA imp for neurla development

19
Q

colipase

A

protein that anchors the pancreatic lipase to the bile acid emusified droplets to help it do its job

20
Q

monoacylglycerol (2-MG)

A

primary digestion products are this + FFA

21
Q

how are med chain triglycerides absorbed

A

directly into cells
dont need bile acids
FA bound to albumin

22
Q

how are cholesterol esters absorbed?

A

they arent
pancreatic cholesterol esterase must make it into free cholesterol
free cholesterol is absorbed after being solubilized in bile salt micelles

23
Q

how much of dietary cholesterol is excreted?

24
Q

describe plant sterol absorption

A

high dietary plant sterols interfere w cholesterol absorption

found in butter-replacement products

25
steatorrhea
fatty and malodorous stools
26
situations assoc w steatorrhea
1. pancreatic disease 2. insufficient bile production - gall bladder, cystic duct obstruction, poor liver secretion 3. loss of lrg seg of small intestine 4. damage to intestinal villae (ie celiac) 5. failure of chylomicron synthesis
27
72h fecal fat test
greater than 7% excretion than intake = fat malabsorption
28
problem w having unabsorbed digestion products like FA in the lumen of the intestine
interfere w absorption of various divalent cations | ie Ca, Mg, Zn
29
what is most imp interms of increased incidence of atherosclerosis
dietary fat | far moreso than cholesterol
30
___ are more atherogenic
saturated FA & trans FA PUFA and MUFA are less atherogenic
31
antiatherogenic
fish oil fatty acids (20:5 and 22:6, omega-3 PUFA)
32
mediterranean diet
?
33
homocysteine and artherosclerosis
correlated for inc risk for cardiovascular disease inc in thrombosis folate normalizes levels B6 B12 deficiencies predispose to hyperhomocysteinemia currently believe CV risk doesnt respond to B-vitamins