Lithium Flashcards
1
Q
What are the important points on Lithium?
A
Mood stabilizer first line
For mania, depression
Acute mania
(Lithium + valproate + antipsychotic + benzodiazepine)
Maintenance
NOT in kidney disease, pregnancy, breastfeeding
Do ECG, RFT, Thyroid, SE, pregnancy test
Monitor blood level every 6 months (0.6-0.8mM)
, thyroid and renal every 12 months
Toxicity at > 1.5 mMol/L
2
Q
What are the drug interactions of lithium?
A
Diuretics ACE inhibitors NSAIDs ARB CCB
3
Q
What are the side effects of lithium and toxicity features?
A
SIDE EFFECTS nausea Diarrhea Fine tremor Polyuria Polydipsia Acne Weight gain Goiter Hypothyroidism Renal impairment Leucocytosis Hyperparathyroidism Hypercalcemia
TOXICITY >1.5 mM Vomiting Diarrhea Coarse tremor Blurred vision Drowsiness Muscle weakness Ataxia Dysarthria
>2.0 mM Hyper reflexia Hyperextension Convulsions Renal failure Heart failure Coma Death
