Liver and glucose homeostasis Flashcards
Why does the liver take non-carbohydrate substrates and synthesise them into glucose?
Maintain plasma glucose
The liver deaminates (removes amino group) amino acids and converts amino groups and ammonia into what?
Urea
The liver synthesises what from cholesterol?
Bile salts
What does the liver do to cholesterol?
Aids to eliminate it from body
Synthesises bile salts from cholesterol
What cells of the pancreas secrete insulin?
B cells
What cells of the pancreas secrete glucagon?
A cells
GLUT 3 is predominantly neuronal. Does this have a high or low affinity for glucose?
High affinity
Allows glucose uptake irrespective of blood glucose concentration
What are the immediate cellular affects of insulin?
Increased rate of glucose uptake in muscle and adipocytes
Modulation of activity of enzymes involved in glucose metabolism
What do the immediate cellular effects of insulin not require?
Protein synthesis
What are the longer lasting cellular effects of insulin?
