Liver/Bili Flashcards

(32 cards)

1
Q

most common cause of cholestasis and treatment

A

obstruction of the biliary tract outside the liver (gallstones, strictures, infection, or ischemia)
cholecystectomy

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2
Q

temporary treatment for acute cholecystitis

A

decompression and drainage of the gallbladder w cholecystectomy tube

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3
Q

6 indications for cholecysectomy

A

symptomatic cholelithiasis, acute cholecystitis, chronic cholecystitis, biliary dyskinesia, GB polyps or carcinoma, choledocholithiasis

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4
Q

what is cholangiography

A

cystic duct is opened and dye is injected into the biliary tree and xrays are taken to identify stones or abnormalities –> CBD exploration to ERCP performed if needed

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5
Q

respiratory considerations with CBD surgery (pre-op)

A

-pain –> reduced FRC, hypoventilation, atelectasis, tachypnea, respiratory alkalosis
-sepsis –> tachypnea & respiratory alkalosis

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6
Q

CV considerations for GB sx

A

-hypovolemia (vomiting, reduced PO intake) –> resuscitate
-exaggerated effects with reverse Trend + insufflation (impaired venous return)
-epigastric discomfort can mimic MI

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7
Q

GI considerations for GB sx

A

-peritonitis, abdominal distension, paralytic ileus
-consider full stomach RSI
-if n/v check electrolytes

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8
Q

what is the sphincter of oddi

A

smooth muscle that surrounds the end of the CBD and pancreatic duct and allows bile to flow into the small intestine during digestion

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9
Q

what meds and conditions can cause sphincter of oddi to spasm

A

opioids
acute cholecystitis (raises GB intraluminal pressure)

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10
Q

what medication is the treatment for sphincter of oddi spasms

A

glucagon 0.5-1mg per surgeon request
–reduces intraluminal pressure of the GB

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11
Q

what is an ERCP

A

-easiest and least invasive way to enter the bile duct to diagnose and treat conditions of the liver, bile duct, and pancreas (stones or stenosis). can relieve obstruction of bile/panc ducts

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12
Q

Respiratory considerations for ERCP

A

-airway eval and assess the need for GETA
-may have limited access to the airway intra-procedure
-if ascites and pleural fluid accumulation –> impaired ventilation and increased aspiration risk

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13
Q

CV considerations for ERCP

A

hypotension and ECG changes are common

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14
Q

hepatic considerations for ERCP

A

coagulopathy, altered drug metabolism, and other metabolic disturbances

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15
Q

renal considerations for ERCP

A

may have ARF (high BUN/Cr) due to volume depletion

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16
Q

in what case may volume depletion be severe and require resuscitation pre-op

A

acute pancreatitis

17
Q

whta type of anesthesia is used for ERCP

A

deep sedation vs GA (if complex, high asp risk, or uncooperative, +/- RSI)

18
Q

Anesthetic Considerations for ERCP
-position
-access
-ETT
-GI
-other

A

-prone with head turned, arms by side
-1 PIV, +/- art line
-risk for R mainstem or extubation by scope
-decompress the stomach
-place bit block and have glucagon available

19
Q

what is the most important predictor of short-term survival s/p hepatic resection

A

intra-op blood loss

20
Q

where does bleed occur from during hepatic resection

A

intrahepatic branches of portal and hepatic veins

21
Q

anatomic vs non-anatomic liver resections

A

anatomic =veins/arteries dissected and mobilized before resection of liver parenchyma.
non-anatomic= only the tumor w 1-2cm margin is removed, not the entire lobe or segment (good for cirrhosis or chronic hepatitis)

22
Q

CV/resp liver resection pre-op considerations

A

-Ascites effect on respiratory mechanics
- tumor size and location may impede venous return
-anticipate high EBL

23
Q

what does the liver produce? except?

A

-all clotting factors ex factor 8
-have coags and T&S

24
Q

Anes for liver resection:
-anes
-lines
-position
-EBL & tx

A

-GETA/RSI/epidural
-2 PIV, art line, foley, +/- CVC & TEE
-supine
-250-750 –> IVF, albumin, blood

25
liver resection: elevated CVP to what
-12mmHg prior to X-clamping
26
liver resection: expect what after major resections and treat with?
-major HD changes -phenylephrine and epi for hypotension
27
anesthetic plan for liver sx blood loss
NS 10-20ml/kg/hr T&S 2uPRBC ready be prepared for MTP (PRBC, FFP, plt, Ca) blood salvage devices
28
CVP strategy for blood loss and liver sx
-intermittent vascular inflow occlusion or total vascular occlusion -CVP < 5mmHg prevents liver congestion and reduces bleeding, increasing the risk of ARF -CVP 7-10 = increased bleeding and transfusion rate
29
pringle maneuver
-a method to control intra-operative blood loss -temporary occlusion of the hepatoduodenal ligament -usually tolerated for 15-20min -rarely used today bc of newer techniques
30
what 3 structures are occluded by occlusion of the hepatoduodenal ligament in the pringle maneuver
portal vein, hepatic artery, and CBD
31
32
laparoscopic liver resection management tips to reduce blood loss
CO2 pneumo to 10-14mmHg lower CVP <5