LIVER PATH 1,2,3 PICTURES

Question 1

Identify the pathology:

Answer 1

Extrahepatic biliary obstruction

Arrow shows a bile duct plug

Question 2

Identify the pathology:

Answer 2

Centrilobular hemorrhagic necrosis (nutmeg liver)

Question 3

ID the pathology:

Answer 3

hepatic infarct

Question 4

Radiation or hepatotoxins can cause this pathology:

Answer 4

Sinusoidal obstruction syndrome

Question 5

Parasite causing this pathology?

Answer 5

Echinococcal cyst

Question 6

Brown pigment these arrows point indicates what exactly?

Answer 6

Cholestasis

Question 7

Picture shows Acute Viral Hepatitis. Arrow points to what?

Answer 7

Councilman body

(hepatocyte undergoing apoptosis)

Question 8

Ground glass. Diagnosis?

Answer 8

Chronic HBV hepatitis

Question 9

ID the path:

Answer 9

Cirrhosis (trimchrome stain)

Question 10

What is the path here? Where region of liver does it originiate in?

Answer 10

Macrovesicular steatosis (initially begins in the centrilobular region)

Question 11

What particular problem do we see with these vertical arrows?

Answer 11

Ballooning degeneration (as part of steatohepatitis)

Question 12

What is the arrowhead pointing to?

The arrow?

Overarchign pathology?

Answer 12

Arrowhead = Neutrophilic inflammation

Arrow = Mallory Body

Path = Steatosis caused by alcoholic liver disease

Question 13

ID the pathology:

Answer 13

Lymphocytic/granulomatous cholangitis in PBC!

Question 14

Dx from this cholangiogram?

Answer 14

PSC

Primary sclerosing cholangitis

Question 15

ID this path specimen:

Answer 15

fibrosing cholangitis

Question 16

Patient’s hemoglobin is abnormal…. then you see this on liver biopsy

Answer 16

hemochromatosis

Question 17

See this on physical exam. What labs will confirm suspicions?

Answer 17

To confirm Wilson’s:

Low ceruloplasmin levels

24 hr urinary copeer excretion increased

overall serum copper is low

Question 18

Cause of this pathological abnormality?

Answer 18

Cytoplasmic globular inclusions

Alpha-1-antitrypsin deficiency!

Question 19

Dx?

Answer 19

Sarcoidosis

Question 20

Diagnosis via this contrast CT?

Answer 20

Hemangioma

Question 21

Dx or this gross specimen?

Answer 21

Focal Nodular Hyperplasia

Question 22

Dx of this gross gallbladder specimen?

Answer 22

Phrygian cap of gallbladder

Question 23

Dx from this specimen stained with reticulin?

Answer 23

Nodular Regenerative hyperplasia

Associated with conditions affecting intrahepatic blood flow

EX: Solid-organ transplatns, bone marrow transplants, and vasculitis

Question 24

Neoplasm dx?

Answer 24

Hepatocellular adenoma

(see confluence of hepatocytes)

Question 25

Dx of gross specimen?

Answer 25

Bile duct hamartoma (mimics metastatic carcinoma)

Question 26

Gross dx?

Answer 26

Biliary mucinous cystadenoma

Question 27

Dx?

Answer 27

HCC Hepatocellular carcinoma

Question 28

Name this variant of HCC:

Answer 28

Fibrolamellar variant of HCC

Question 29

This patient presented with gallstones seen on US. Dx?

Answer 29

Chronic Cholescystitis | (see the lymphocytic inflammation?)

Question 30

This patient also presented with gallstones on US. Dx?

Answer 30

Acute Cholecystitis (see neutrophilic inflammation?)

Question 31

Dx for this condition?

Answer 31

cholesterolosis

Question 32

Dx?

Answer 32

Extrahepatic cholangiocarcinoma of the common bile duct