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Q

Describe the INTERSTROKE study

Context: How risk factors from unhealthy behaviours influence health outcomes

BR 22

Yusuf S,Lancet 2016:388(10046)761-775.

A

Design: International case-control study

Population: 26,919 subjects (13,447 with stroke [ischemic & hemorrhagic], 13,472 controls) with acute first stroke.

  • from 32 countries in Asia, American, Europe, Australia, Middle East, Africa
  • Looked at odds ratios of multiple risk factors for stroke and population attributable risk (PAR).
  • all 10 risk factors account for 90% of PAR in men & women.
  • similar associations noted in men/women, old/young, all regions of the world.

Mnemonic: ESCAPED

E - Exercise

S - Smoking

C - CV - Htn, lipids, cardiac (afib)

A - Alcohol

P - Stress

E - Endo - DM, waist-hip ratio

D - Diet