LOCAL ANESTHETICS Flashcards
LOCAL ANESTHETICS
ESTERS
AMIDES
ESTERS
one ‘i’
PROCAINE, NOVOCAINE, CHOLOPROCAINE
BENZOCAINE, BUTAMBEN
COCAINE
TETRACAINE
AMIDES
two ‘i’
LIDOCAINE
PRILOCAINE, MEPIVACAINE
BUPIVACAINE, LEVOBUPIVACAINE
ROPIVACAINE
Local anesthetic with the shortest half-life
PROCAINE
Local anesthetic with the longest half-life
ROPIVACAINE
MOA: Local Anesthetics
Block VG Na channels preventing depolarization
Ester with intrinsic sympathomimetic activity causing vasoconstriction. Does not need to be injected with epinephrine.
COCAINE
Special SE of Benzocaine and Butamben
Methemeglobinemia
TRUE OR FALSE
All local anesthetics are vasodilators except COCAINE.
TRUE
Ester used primarily for spinal anesthesia
TETRACAINE
Ester causing mood elevation due to action on dopamine receptor
COCAINE
Ester used in surgeries involving ear, nose and throat
Cocaine
Ester also available as opthalmic solution
TETRACAINE
AMIDE used as anti-arrhythmic
LIDOCAINE
AMIDE used in dental procedures
PRILOCAINE, MEPIVACAINE
Special SE of Lidocaine
Transient Neurological Symptoms, Cauda Equina Syndrome
Most cardiotoxic out of all LA
BUPIVACAINE
LEVOBUPIVACAINE
Treatment for cardiotoxicity by Bupivacaine and Levobupivacaine
INTRALIPID/LIPOSOMAL FORMS
TRUE OR FALSE
Most local anesthetics are weak bases.
TRUE
TRUE OR FALSE
Alkalinizing the site with bicarbonate will hasten the onset of action of local anesthetics.
TRUE
LOCAL ANESTHETIC SYSTEMIC TOXICITY (LAST) Treatment
Intralipid (Lipid Emulsion Therapy)
