Localization

Question 1

Lesion in amygdala (bilaterally)

Answer 1

Kluver-Bucy syndrome: Hyperphagia, hypersexuality, hyperorality.

Associated w/ HSV-1

Question 2

Lesion to frontal lobe cortex

Answer 2

Disinhibition, poor concentration/orientation/judgment, reemergence of primitive reflexes

Question 3

Lesion to non-dominant parietal lobe

Answer 3

Hemineglect

Question 4

Lesion to dominant parietal lobe

Answer 4

Agraphia, acalculia, finger agnosia, left-right disorentation

“Grestmann syndrome”

Question 5

Lesion to reticular activating system in midbrain

Answer 5

Coma

Question 6

Lesion to bilateral mamillary bodies

Answer 6

Wernicke-Korsakoff syndrome: Confusion, opthalmoplegia, ataxia; memory loss, confabulation, personality changes. Assoc w/ thiamine (B1) deficiency in alcoholics

Question 7

Lesion to basal ganglia

Answer 7

–> Parkinsons, Huntington, depending on where

Question 8

Lesion to cerebellar hemisphere

Answer 8

Limb ataxia, intention tremor, loss of balance

Question 9

Lesion to cerebellar vermis

Answer 9

Truncal ataxia, dysarthria

Question 10

Lesion to subthalamic nucleus

Answer 10

Contralateral hemiballismus

Question 11

Lesion to bilateral hippocampi

Answer 11

Inability to make new memories

Question 12

Lesion to paramedian pontine reticular formation

Answer 12

Eyes look away from lesion

Question 13

Lesion to frontal eye field

Answer 13

Eyes look toward lesion