Long Term Control Of Blood Pressure Flashcards Preview

CVS physiology > Long Term Control Of Blood Pressure > Flashcards

Flashcards in Long Term Control Of Blood Pressure Deck (19):
1

What does the long term control of blood pressure revolve around?

The control of plasma volume by the kidney through 3 hormonal systems;
Renin angiotensin aldosterone system
Anti diuretic factor ADH
Atrial nautriuretic peptide

2

The regulation of plasma volume by the kidneys is known as what system?

The renal counter current system

3

What receptors detect plasma volume in the kidneys?

Atrial volume receptors which are low pressure baroreceptors

4

When the collecting duct is impermeable what does this result in?

Little water absorption , lots of urine and a reduction in plasma volune
= large volume of hypo osmotic urine

5

Where is renin produced from?

The juxtoglomerular of kidney

6

What is renin production stimulated by?

Activated by a decrease in MAP through;
Activation sympathetic nerves to juxtoglomerular apparatus
Decreased distension of afferent arterioles
Decreased delivery of sodium and chlorine through tubule

7

What is the role of renin?

Renin converts angiotensin to angiotensin II

8

What is the action of angiotensin II?

Stimulates release of aldosterone from adrenal cortex
Increases release of ADH from pituitary
Vasoconstrictor

9

Where is anti diuretic hormone synthesised and produced?

The hypothalamus and produced in the pituitary

10

What is ADH release triggered by?

Decrease in MAP which is signalled by;
Decrease in blood volume
Inxrease in osmolarity of interstitial fluid
Circulating angiotensin II

11

What is the action of ADH?

Increases permeability of the collecting duct to water and therefore reduces diuresis and increases plasma volume
Causes vasoconstrition and therefore increases MAP

12

Where is atrial natriuretic peptide produced and released from?

ANP is produced and released from the myocardial cells of the atria

13

What is ANP release triggered by?

ANP is stimulated by a rise in MAP which is detected by;
Increased distension of atria

14

What is the action of ANP?

Increases excretion of sodium
Exhibits the release of renin
Acts on medullary cardiovascular centers to reduce MAP

15

what is produced from the juxtoglomerular apparatus of the kidney?

renin

16

what detects a decreased distension of afferent arterioles?

angiotensin II

17

what causes an increase excretion of Na?

ANP

18

What is detected by a decrease in blood volume?

ADH

19

where is aldosterone produced from?

the adrenal cortex