lower resp tract infection- adults Flashcards

(43 cards)

1
Q

What is defined as part of the lower respiratory tract?

A

below the vocal cords

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2
Q

what does pneumonia involve?

A

parenchyma of the lungs

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3
Q

what is empyema?

A

pus

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4
Q

what is a lung abscess?

A

walled off cavity of infection and usually contains pus as well but in smaller area - develops thick skin around it.

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5
Q

what is bronchiectasis?

A

bronchi become dilated and inflamed- chronic condition.

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6
Q

Give characteristics of acute bronchitis?

A

inflammation of bronchi
temporary <3 weeks
cough and sputum
usually viral
main management - fluids, paracetamol

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7
Q

How long is chronic bronchitis present for>

A

cough lasting 3 months of the year for at least 2 years in a row

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8
Q

Give characteristics of a COPD exacerbation?

A

change in colour and amount of sputum
fevers
increased breathlessness
wheeze
cough

streptococcus pneumoniae
haemophilus influenzae
moraxella catarrhalis
viral

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9
Q

treatment for COPD exacerbation?

A

steroids - reduce inflammation antibiotics - effective or non effective
maybe nebulisers if severe

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10
Q

What are the different types of pneumonia?

A

bronchopneumonia
lobar pneumonia
interstitial pneumonia - viral usually

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11
Q

What does consolidation lead to?

A

solidification due to cellular exudate in alveoli leads to impaired gas exchange

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12
Q

what are risk factors for pneumonia?

A

smoking
alcohol to excess
extremes of age
preceding viral illness
pre-existing lung disease
chronic illness
immunocompromised
hospitalisation
IVDU

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13
Q

What are the symptoms of pneumonia?

A

fever (normal is 37 +/- 0.6 )
rigors (shivers)
myalgia (pain in muscles)
cough and sputum (rusty brown sputum= streptococcus pneumoniae)
chest pain (pleuritic)
dyspnoea
haemoptysis

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14
Q

Signs of pneumonia?

A

tachypnoea
tachycardia
reduced expansion
dull percussion
bronchial breathing
crepitations (snapping open of alveoli)
vocal resonance (goes up over areas of consolidation)

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15
Q

Investigations for pneumonia in the community?

A

may be none
CXR if in doubt or not improving

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16
Q

Investigations in hospital for pneumonia?

A

blood count , look for inflammatory marker called C reactive protein
blood cultures are helpful esp if febrile
sputum culture to try and identify the underlying bacteria
viral throat swab to see if viral cause or viral preceding infection- led to bacterial
legionella urinary antigen is also helpful to test for atypical organisms

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17
Q

Differential diagnosis for pneumonia?

A

tuberculosis
lung cancer
pulmonary embolism
pulmonary oedema
pulmonary vasculitis

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18
Q

What is the most common bug that causes pneumonia?

A

streptococcus pneumonia

19
Q

What are the typical community acquired pneumoniae?

A

streptococcus pneumoniae
haemophilus influenzae
mycoplasma pneumoniae (4-5 year cycles, extra pulmonary complications)

20
Q

What are the A-typical community acquired pneumoniae?

A

more systemic, more dry cough, less sputum production and general malaise , headaches , confusion, muscles aches , sometimes diarrhea and vomiting

legionella pneumophilia (air con, fresh water)
chlamydia pneumoniae (CAD)
chlamydia psittaci (birds)
coxiella burnetti (farm animals)
moraxella cattarhalis (COPD)
viruses (influenza, RSV , SARS, varicella)

21
Q

What are the types of bacteria that cause nosocomial (hospital acquired pneumonia?

A

enterobacteria (aspiration)
staphylococcus aureus (after flu infection)
pseudomonas aerigunosa
klebsiella pneumoniae (aspiration and more common in alcoholics)
clostridia
anaerobes
TB

22
Q

What is the common scoring system used for pneumonia?

23
Q

What does CURB 65 stand for?

A

C- confusion
U- blood urea > 7mmol/L
R- Respiratory rate more or 30/ min
B- systolic BP< 90 mmHg, diastolic <60mmHg
65 - age 65 or older

score -1 point for each of these features

24
Q

A score using CURB 65 indicates what?

A

0-1- low risk and could be treated in community
2- moderate risk- hospital treatment usually required
3-5 - high risk of death and need for ITU

25
What to be wary of if using CURB 65?
young people hypoxia multi-lobar consolidation
26
How is pneumonia treated?
antibiotics- mainstay of treatment penicillin - cover broad spectrum do they need IV ( if sepsis signs or route compromised) or oral antibiotics supportive management (oxygen, fluid , antipyretics and for severe intubation and ventilation)
27
What antibiotics used?
CURB 0-1- Amoxicillin (if penicillin allergy - clarithromcyine or doxycycline) CURB 2 - Amoxicillin and clarithromycin (atypicals) (if penicillin allergy- levofloxacin) CURB 3-5- Co-amoxiclav + clarithromycin (atypicals) ( if penicillin allergy - levofloxacin or co-trimoxazole) duration of 5 days (CURB 0-1 ), 5-7 days (CURB 2 ) , 7-10 days (CURB 3-5)
28
What can influenza lead on to?
staphylococcus aureus secondary infection
28
Where does aspiration pneumonia occur?
in conditions where people can't swallow properly - stroke -Multiple Sclerosis -Myasthenia Gravis - sedation -oesophageal disease -anaerobic infections -amoxicillin and metronidazole
29
What can immunocompromised people develop?
(haematological malignancy, neutropenia, HIV) fungi- aspergillus, candida , cytomegalovirus, HSV or varicella
30
What is MRSA treated with?
vancomycin
31
Complications of pneumonia?
* Sepsis * Acute Kidney Injury * Adult Respiratory Distress Syndrome * Parapneumonic effusion * Empyema * Lung Abscess * Disseminated infection
32
signs of complicated pneumonia?
Swinging fever Sweats Persistently high WCC / CRP Weight loss Failure to improve
33
How to diagnose parapneumonic effusion/ empyema?
investi: CXR, thoracic ultrasound, needle aspirate of fluid measurements: check pH (complicated if pH<7.2 Empyema -pus/Culture +ve
34
treatment of parapneumoic effusion/empyema?
* May need drain + prolonged abx Lung Abscess
35
Causes and symptoms of lung absess?
More likely with Staph aureus, pseudomonas, anaerobes… * Purulent sputum, haemoptysis
36
Investigations for lung absess AND treatment ?
Screen for TB * CT scan +/- bronchoscopy prolonged abx
37
when should repeat CXR?
if over 50 years old and smokers
38
what to do if recurrent pneumonia?
* Immunocompromised? * Underlying structural lung disease? * Aspiration?
39
causes of bronchiectasis?
* Idiopathic * Childhood infection * CF * Ciliary dyskinesia * Hypogammaglobulinaemia * Allergic Broncho Pulmonary Aspergillosis (ABPA)
40
symproms/ signs of bronchiectasis?
* Chronic productive cough * Breathlessness * Recurrent LRTI * Haemoptysis * Finger clubbing * Crepitations (coarse) * Wheeze
41
what could infective exacerbations be caused by?
o Staph aureus o Haemophilus influenzae o Pseudomonas aerigunosa
42
treatment and investigations for bronchiectastis?
o Sputum Cxessential (including AAFB) o Chest physio o Mucolytics o Prolonged antibiotic course 10-14 days o Vaccinations o Consider prophylactic abx * Obstructive spirometry