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lp 6 Flashcards

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1
Q

doze in care se poate asocia adrenalina pt anestezice locale

A

1/ 50.000-1/ 200.000

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2
Q

date despre lidocaina

A
  • anestezic local
  • durata medie de actiune
  • potenta medie
  • act prin inhibare propagare impuls nervs ca urmare a scadere permeab mb la ioni Na
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3
Q

date despre adrenalina in combinatie cu lidocaina

A
  • reduce efect vasodilatator lidoc
  • creste intensitate si durata anestezie
  • scade risc sangerare
  • scade toxicitate lidoc
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4
Q

lidocaina utilizata singura ca anestezie

A

=xilina
* solutie 1%- fiole de 10ml si 20 ml
* solutie 2%- fiole de 2ml
* solutie 4%- fiole de 2 ml

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5
Q

principalii alcaloizi din opiu

A
  • codeina
  • morfina
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6
Q

compusi sintetici inruditi cu morfina

A
  • fentanyl
  • tramadol
  • metadona
  • petidina ( mialgin)
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7
Q

tip formular prescriere morfina

A

galben

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8
Q

forme farmaceutice morfina

A
  • fiole- morfina clorhidrica/ sulfurica - 1 fiola=20 mg mrofina
  • cpr obisnuite- Sevredol
  • cpr retard- Vendal
  • preparate de opiu-tinctura opiu (1% morfina) si pulbere opiu( 10%)
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9
Q

mecanism actiune morfina

A

agonist pe receptori opioizi- receptori endorfinici
ii stimuleaza

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10
Q

efecte morfina

A
  • analgezic
  • sedativ
  • anxiolitic intens
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11
Q

dureri acute intense care necesita morfina

A
  • dureri postop
  • dureri fracturi
  • durere infarct acut miocard
  • durere colica renala- preferabil asociat cu ATROPINA care contracareaza efect spastic morfina pe musc netd
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12
Q

ce forme de morfina se utilizeaza in durere cronica( neoplazii)

A

Sevredol- cpr cu elib imediata
Vendal- cpr retard
*uneori pompe automate de perfuzie

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13
Q

efecte codeina

A

analgezic
antitusiv

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14
Q

doze adm codeina ca analgezic

A
  • singura: pana la 30-50 mg o data
  • asociata cu Paracetamol, Ibuprofen, Aspirina: 10-30 mg o data
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15
Q

pe ce se prescrie codeina

A

formular verde

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16
Q

de ce nu se administreaza morfina in durere reumatica

A

raspuns la morfina slab

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17
Q

utilizare fentanyl

A
  • anestezic injectabil iv
  • analgezie in dureri neoplazice
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18
Q

forme fentanyl utilizate ca analgezice pt dureri neoplazice

A
  • plasturi- se schimba la 3 zile
  • cpr pt supt- sublingual la nev
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19
Q

cum se adm tramadol

Study These Flashcards
A

adm orala/ inj
dureri intensitate medie
-risc dependenta mic

20
Q

forme tramadol

Study These Flashcards
A
  • cps
  • cpr retard
  • fiole
21
Q

preparate care asociaza tramadol cu paracetamol

Study These Flashcards
A
  • Doreta
  • Zaldiar
22
Q

variante doreta

Study These Flashcards
A
  • cpr 37,5/ 325 mg
  • cpr 75/650mg
23
Q

variante zaldiar

24
Q

preparate care asociaza codeina cu un analegzic non opioid

Study These Flashcards
A
  • Codamin P
  • Nurofen Plus 200/12,8 mg
25
cum se mai numesc analgezicele antipiretice antiinflamatoare nesteroidiene
pe scurt- antiinflamatoare nesteroidiene (AINS)
26
mecanism actiune AINS
INHIBARE CICLOOXIGENAZA =>scadere sinteza prostaglandine+ tromboxan
27
cum se explica efect antiinflamator si analgezic AINS
scadere sinteza PG tesut afectat *posibil contribuie si inhibare COX nivel central
28
cum se explica efect antipiretic AINS
urmare a inhibare sinteza de prostaglandine hipotalamus (m ales PGE2)
29
forme ciclooxigenaza
* COX 1= enzima constitutiva * COX 2= enzima inductibila sunt izoforme
30
actiune COX1
determina sinteza de prostaglandine cu rol fiziologic: * PG mentinere fct renala * PG protectie muc gastrica
31
actiune COX2
produsa sub actiune citokine elib in proces inflam si stari febrile
32
inhibarea carei izoforme COX explica efect analgezic, antipiretic, antiinflam
COX2
33
inhibitoare selective COX2
* celecoxib (celebrex) * etoricoxib (arcoxia) * parecoxib
34
efect acid acetilsalicilic in fct de doza
* medii (1- 2 g pe zi) : analgezic+ antipiretic * mari (>3g/zi): antiinflamator-rar * mici (75-100mg/zi): antiagregant plachetar
35
preparate comerciale acid acetilsalicilic
* Aspirina 500 mg * cpr efervescente * preparate tamponate- cu gluconat/ carbonat de calciu
36
ce au paracetamol sinus si paracetamol plus pe langa paracetamol
* antihistaminic anti H1 * vasoconstrictor pseudoefedrina
37
forme farmaceutice naproxen
* Nalgesin 220 mg * Naldorex 275 mg * Nalgesin Forte 550 mg * Vimovo= naproxen+esomeprazol 500/20mg
38
cand se foloseste naproxen
dureri reumatice cronice
39
forme de arcoxia si cand se folosesc
* cpr 30 mg- boala artrozica * cpr 60 mg- boala artrozica daca 30mg nu a fost eficient * cpr 90 mg- boli reumatice severe+ dupa interventii chir dentare * cpr 120 mg- artrita gutoasa- maxim 8 zile
40
AINS utile in/ dupa interventii stomatologice
* Ibuprofen * Naproxen (Nalgesin) * Acid mefenamic (Vidan) * Etoricoxib (Arcoxia) * Ketorolac
41
utilizare Ibuprofen in stoma
400 mg de 3 ori pe zi la distanta de minim 4-6 ore
42
utilizare Naproxen in stoma
1 cpr 220mg la 8-12 ore maxim 3 cpr pe zi
43
utilizare acid mefenamic in stoma
Cp 500 mg 1 cp de 3 ori pe zi
44
utilizare etoricoxib in stoma
cpr 90 mg 1 cp/zi, maxim 3 zile
45
utilizare ketorolac in stoma
cp 10 mg 2-4 cp/zi dupa unele interventii

farmaco (27 decks)

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