Lung Cancer Flashcards

1
Q

What are the types of lung cancer ?

A

Non-small cell
Small cell
Mesothelioma
Neuroendocrine

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2
Q

What are some risk factors for lung cancer ?

A

Smoking
Lung disease - TB and COPD
Radiotherapy
Toxins - asbestos, radon gas and arsenic
Pulmonary fibrosis
HIV
Family history

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3
Q

What are some symptoms of lung cancer ?

A

Cough
Haemoptysis
Dyspnoea
Chest pain
Recurrent chest infections
Weight loss
Anorexia
Fatigue

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4
Q

What are some signs of lung cancer ?

A

Cachexia
Clubbing
Anaemia
Lymphadenopathy - axilla, supraclavicular
Chest - pleural effusion, consolidation
SVCO
Horner’s syndrome

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5
Q

What are some criteria for an urgent CXR ?

A

Age over 40 + ( 2 of the following )
- cough
- fatigue
- SOB
- chest pain
- weight loss
- anorexia
( smoking is +1)

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6
Q

What is associated with small cell lung cancer ?

A

Paraneoplastic disease

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7
Q

What is the management of small cell lung cancer ?

A

Surgery
Chemotherapy
Radiotherapy

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8
Q

What are the most common non-small cell lung cancers and where do they arise from ?

A

Adenocarcinoma- glands lining the lungs
Squamous cell carcinoma - flat cells over surface of the airways

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9
Q

What is stage 1 lung cancer ?

A

The cancer is small ( 3 - 5 cm )
No spread to the lymph nodes

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10
Q

What is stage 2 lung cancer ?

A

The tumour is larger than 5cm and there is spread to nearby lymph nodes

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11
Q

What is stage 3a lung cancer ?

A

The cancer extends into surrounding tissues and structures ( lining of the lung and chest wall - ipsilateral lymph nodes )

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12
Q

What is stage 3b lung cancer ?

A

More than 2 tumours
Spread to contralateral lung and lymph nodes

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13
Q

What is stage 4 lung cancer ?

A

Metastatic spread to other parts of the body - brain, bone, liver and adrenal glands

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14
Q

What is the management of stage 1/2 lung cancer ?

A

Surgery
Adjuvant chemotherapy

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15
Q

What is the management of medically inoperable stage 1/2 lung cancer ?

A

Radical radiotherapy

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16
Q

What is the management of metastatic lung cancer ?

A

Chemotherapy
Targeted therapy
Immunotherapy

17
Q

What lung cancers can benefit from biological or targeted therapy ?

A

Non-squamous tumours

18
Q

How does Horner’s syndrome present ?

A

Ipsilateral -
. Ptosis
. Miosis
. Anhydrosis
. Enophthalmus

19
Q

What causes horners syndrome ?

A

Compression of the sympathetic ganglion
Associated with pancoast tumour

20
Q

Which cancer is associated with pancoast tumour ?

A

Non-small cell lung cancer

21
Q

What can a pancoast tumour compress ?

A

Brachiocephalic vein
Phrenic nerve
Subclavian artery
Recurrent laryngeal nerve
Vagus nerve
Sympathetic ganglion

22
Q

What are some symptoms of a pancoast tumour ?

A

Symptoms of lung cancer
Pain / weakness in muscles of hand and arm
Hoarse voice
Bovine cough
SVCO

23
Q

How is a pancoast tumour managed ?

A

Surgery
Chemotherapy
Radiotherapy