Lung Cancer & Metastatic Disease

Question 1

How does a Pancoast’s tumour present?

Answer 1

• Horner’s syndrome features (unilateral meiosis, ptosis, anhidrosis)
• headaches
• shoulder pain (no cough)

Question 2

What are the causes of Horner’s syndrome?

Answer 2

Pre-ganglionic - Pancoast’s, brachial plexus injury
Central - hypothalamic stroke, syringomyelia
Post-ganglionic - CAD (neck pain), basal skull fractures

Question 3

What biochemistry is indicative of SCC?

Answer 3

Hypercalcaemia (on bg of smoking hx)