Lung Cancer part 1

Question 1

What are pros and cons of nicotine patch, gum, etc.?

Answer 1

• reduces chances of lung cancer

- does not reduce risk of ischemic heart disease

Question 2

What are the types of primary lung cancer?

Answer 2

• Non-small cell lung cancer (NSCLC) 80% are this

- Small cell lung cancer (SCLC) 20% are this type

Question 3

What are the types of Non-small cell lung cancer (NSCLC)?

Answer 3

• squamous cell carcinoma (SCC)
• adenocarcinoma
• large cell

Question 4

• 25-30% of all lung cancers
• slow growing tumors in central part of lung (epidermal growth factor)
• most often associated with hypercalcemia
• detectable with cytologic studies and visible on x-ray

Answer 4

squamous cell carcinoma which is a (NSCLC)

Question 5

• 35-40% of all lung cancers
• often peripheral location in lung
• most common subtype in non-smokers
• moderate growth rate and does NOT respond well to chemo
• has its own subtype

Answer 5

adenocarcinoma which is a (NSCLC)

-subtype is bronchoalveolar: produces voluminous watery sputum

Question 6

• 10-15% of all lung cancers
• manifestations as large peripheral mass on radiography
• rapid growth that is highly metastatic

Answer 6

Large-cell carcinoma which is a (NSCLC)

Question 7

• 20% of lung cancers
• highly metastatic frequently to brain
• very raid growth
• chemo does not help
• radiation of palliative measures

Answer 7

small cell lung cancer (SCLC)

Question 8

How do lung cancer tumors progress and grow?

Answer 8

• by amplification of oncogenes
• RAS family have important abnormalities
• mutation of RAS NOT seen in non-smokers

Question 9

What are the diagnostic studies for lung cancer?

Answer 9

• chest x-ray: 1st test
• CT: extend of involvement and lymph enlargement
• MRI
• PET: cancer eats the glucose and lights up. No IVF with dextrose for 8-24hr before

Question 10

What IVF needs to be stopped for 8-24 hr before a PET scan.

Answer 10

no IVF with dextrose