Lymph sys

Question 1

What are the components of the lymphatic system?

Answer 1

Spleen
Lymph nodes
Lymphatic vessels

Question 2

Organs of the lymphatic sys

Answer 2

Primary: Bone marrow + Thymus
Secondary: Lymph nodes + spleen

Question 3

The organ with the largest collection of lymphatic tissues in adults is the

Answer 3

Spleen

Question 4

Lymphatic Tissues

Answer 4

Specialized form of connective tissue that contains lymphocytes + other immune cells, which help defend the body against pathogens

Question 5

Thoraic Duct

Answer 5

Drains lymph from the lower body + left upper body into left subclavian vein

Question 6

Right lymphatic duct

Answer 6

Drains lymph from the right upper body into right subclavian vein

Question 7

Cisternae chyli

Answer 7

a dilated sac at the base of the thoracic duct that receives lymph from the lower body + intestines

Question 8

Functions of the Lymphatic sys

Answer 8

Transport excess fluid + protein back to blood stream
Defend body against pathogens
Distribute hormones, nutrients, waste products
Transport dietary fats

Question 9

Types of lymphocytes

Answer 9

T cells
B cells
Natural Killer (NK) cells

Question 10

% of lymphocytes in WBCs

Answer 10

20-40%

Question 11

Organs involved in lymphocyte production + maturation

Answer 11

Produced: Bone marrow
Mature: T cells - Thymus + B cells- Bone marrow

Question 12

Where lymphocytes can NOT be found

Answer 12

Central Nervous system (CNS)

Question 13

Classes of lymphocytes + their production sites

Answer 13

T cells: Produced in bone marrow + mature in thymus
B cells: produced + mature in Bone marrow
NK cells: produce in bone marrow

Question 14

Types of T cells

Answer 14

Helper T cells
Cytotoxic T cells
Suppressor T cells

Question 15

Helper T cells

Answer 15

Activate B cells + other immune cells

Question 16

Cytotoxic T cells

Answer 16

Destroy infected or abnormal cells

Question 17

Suppressor T cells

Answer 17

Regulate + suppress immune responses

Question 18

T cell activation

Answer 18

Activated by recognizing antigen presented by MHC proteins on antigens presenting cells (macrophages)

Question 19

Types of B cells

Answer 19

Plasma B cells
Memory B cells

Question 20

Plasma B cells

Answer 20

Produce antibodies

Question 21

Memory B cells

Answer 21

Provide long term immunity

Question 22

B cell activation

Answer 22

Activated by binding to antigens + receiving signals from helper T cells

Question 23

Lymphoid nodules

Answer 23

Small, localized collections of lymphoid tissues
Filters lymph, remove pathogens, activate immune response

Question 24

Thymus

Answer 24

Secretes hormone Thymosin, which stimulates T cells maturation

Question 25

Spleen

Answer 25

Filters blood + removes old + damaged RBCs Stores blood + Platelets Initiates immune response by activating B + T cells

Question 26

Non specific Defense

Answer 26

Repel all microorganism equally Do NOT target specific pathogens

Question 27

Types of Non specific defense

Answer 27

Physical barriers Phagocytes Immunological surveillance Interferons Inflammation Fever

Question 28

Physical barriers

Answer 28

Skin Mucous mem

Question 29

Phagocytes

Answer 29

Engulf + destroy pathogens

Question 30

Immunological surveillance

Answer 30

NK cells detect + destroy abnormal cells

Question 31

Interferons

Answer 31

Proteins that inhibit viral replication

Question 32

Inflammation

Answer 32

Localized response to injury / infection

Question 33

Fever

Answer 33

Increase in body temp to inhibit pathogen growth

Question 34

Specific defense

Answer 34

Targets specific pathogens + involves activation of lymphocytes (B + T Cells ) Characteristics: Specific, Memory, Versatility, Tolerance

Question 35

Cell responsible for cell mediated immunity

Answer 35

T cells

Question 36

Cells responsible for antibody mediated immunity

Answer 36

B cells

Question 37

Types of immunity

Answer 37

Innate immunity Acquired immunity

Question 38

Innate immunity

Answer 38

In you Genetically determined immunity

Question 39

Acquired immunity

Answer 39

Acquired through antibodies from another source (mother milk or injection)

Question 40

MHC class proteins

Answer 40

MHC class I MHC class II

Question 41

MHC class I

Answer 41

Found on ALL nucleated cells Present intracellular antigens to cytotoxic T cells

Question 42

MHC class II

Answer 42

Found on antigens presenting cells (macrophages) Present extracellular antigens to helper T cells

Question 43

Antibodies

Answer 43

Proteins produced by B cells that recognize + bind to specific antigens Produced by Plasma B cells Neutralize pathogens, activate complement, mark pathogens for destruction

Question 44

IgG antibody

Answer 44

Most abundant Long term Immunity

Question 44

Classes of antibodies

Answer 44

IgG IgM IgA IgE IgD

Question 45

IgM antibody

Answer 45

First antibody produced during infection

Question 46

IgA antibody

Answer 46

Found in secretion (saliva, breast milk)

Question 47

IgE antibody

Answer 47

Involved in allergic reactions

Question 48

IgD antibody

Answer 48

Found on B cell surfaces, involved in B cells activation