Lymphatic/immune Flashcards
Innate immunity
(Non-specific)
1)block entry into blood
2)non-specific-cell meditated responses to rid
of solid pathogen.
*response is not strain specific (attack all)
*neutrophils, eosinophils, basophils,
monocytes, leukocytes, epidermis, NK
cells
Lymphatic functions:
1) Assists the CV system by collecting filtrate
(plasma) that did not get reabsorbed.
2) Assist the immune system by:
* help maturing some leukocytes
* provide mobility for leukocytes
* helps destroy leukocytes (old/worn out)
3) Assists the digestive system by helping
package large hydrophobic fats.
Adaptive immunity
(Specific, acquired)
1) B-lymphocytes
2) T-lymphocytes
3) Antibodies: y shaped protein = 4 polypeptides= 2 heavy chain & 2 light chain
6 functions of activated antibody:
1) agglutination
2) neutralization
3) precipitation
4) Opsonization
5) Activation of natural killer cells
6) Activate the complement system
Agglutination
Bind & clump together antigen-containing pathogen
Neutralization
Pathogen covered with antibodies–> block normal infection activity of pathogen
Precipitation
Clumped antigens fall out of solution; preventing movement through BV
Opsonization
Antibody serves as a beacon/flag to our phagocytize cells
Activation of Natural Killer cells
Destroy abnormal cells
Activate the complement system
30 complement proteins in blood which bind to activated antibodies.
Functions of component:
1) further signal opsonization
2) result in the formation of infected cell or
pathogen
3) inflammation
4) Attach pathogen to an RBC erythrocyte –>liver/spleen–>rid of pathogen
Tonsils
Defense against pathogens in air/food
Pharyngeal/palatine/lingual
Thymus function
Maturation of T lymphocytes
Spleen function
Reservoir for platelets-removes erythrocytes
Filters blood for foreign materials
Appendix function
No function? Safe house for bacteria?
Lymphatic vessels function
Bring lymph into lymph nodes
