lymphatic system Flashcards

(71 cards)

1
Q

what is the main goal/purpose of the lymphatic system

A

brings back escaped fluid (lymph) back into the blood

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2
Q

pick up excess fluid that escaped from the blood. It will return it to the blood.

A

lymphatic vessels

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3
Q

site where gas exchange happens. Weave between tissue cells and blood capillaries.

A

lymphatic capillaries

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4
Q

Carry lymph to and away from lymph nodes

A

lymphatic collecting vessels

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5
Q

drains the lymph from the right arm and the right side of the head and thorax

A

right lymphatic duct

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6
Q

drains lymph from the rest of the body

A

thoracic duct

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7
Q

filter lymph before it is returned to the blood.

A

lymph nodes

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8
Q

engulf and destroy bacteria, viruses, and other foreign substances in lymph

A

macrophages

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9
Q

respond to foreign substances in lymph.

A

lymphocytes

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10
Q

contains follicles for the collection of lymphocytes. Germinal centers enlarge when antibodies are released by plasma cells.

A

cortex (outer part)

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11
Q

inner part of lymph nodes that contain phagocytic macrophages

A

medulla

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12
Q

filters and cleans blood of bacteria, viruses, debris and provides a site for lymphocyte proliferation and immune surveillance.
- destroys worn out blood cells

A

spleen

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13
Q

produces T-lymphocytes

A

thymus

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14
Q

small masses of lymphoid tissue deep to the mucosa surrounding the pharynx that trap and remove bacteria and other foreign pathogens

A

tonsils

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15
Q

results when the tonsils become congested with bacteria

A

tonsilitis

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16
Q

macrophages that destroys and captures bacteria in the intestine

A

peyer’s patches

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17
Q

acts as a sentinel (indicator of the presence of a disease)

A

mucosa - associated lymphoid tissue (MALT)

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18
Q

captures and stores the bacteria of the body

A

appendix

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19
Q

physical, chemical and cellular barriers

A

innate immunity

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20
Q

immunity you develop after being exposed to an infection or from getting a vaccine (chicken pox, covid)

A

active immunity

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21
Q

immunity acquired from someone else or something else

A

passive immunity

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22
Q

first line of defense

A

surface membrane bariers
(skin and mucous membrane)

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23
Q

What protective substances do surface membrane secrete

A
  • acidic secretions
  • sebum
  • acidic gastric juice
  • lysozyme of saliva and tears
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24
Q

internal defense / second line of defense

A

cells and chemicals

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25
Controls several types of tumors and microbial infections by limiting their spread and subsequent tissue damage
natural killer cells
26
enzymes being released to degrade target cell contents
perforin and granzymes
27
cardinal signs of inflammatory response
- Redness - Heat - Pain - Swelling (edema)
28
Chemicals that cause blood vessels to dilate
histamine and kinin
29
fused with a lysosome and enzymes to digest the cell's content
phagocytic vesicle
30
Attack microorganisms directly and Hinders the reproduction of microorganisms
antimicrobial proteins
31
holes and pores in cells causing it to burst
membrane attack complexes (MACs)
32
- at least 20 plasma proteins that circulate in the plasma Activated when these plasma proteins encounter and attach to cells (complement fixation)
complement protein
33
Small proteins secreted by virus-infected cells - Bind to membrane receptors on healthy cell surfaces to interfere with the ability of viruses to multiply
interferons
34
Abnormally high body temperature as a systemic response to invasion by microorganisms
fever
35
third line of defense
adaptive defense system
36
recognizes and acts against particular foreign substances
antigen-specific
37
immunity is not restricted to the initial infection site
systemic
38
immune system recognizes and mounts a stronger attack on previously encountered pathogens.
memory
39
antibody-mediated immunity. Provided by antibodies present in body fluids
humoral immunity
40
Target virus-infected cells, cancer cells, and cells of foreign grafts (transplants)
cellular immunity
41
any substance capable of exciting the immune system and provoking an immune response
antigens
42
Presence in another person’s body can trigger an immune response. - reason for transplant rejection
self-antigens
43
When they link up with proteins, the immune system recognize the combination as foreign and respond with an attack
haptens
44
produce antibodies and oversee humoral immunity
B lymphocytes
45
constitute the cell-mediated arm of the adaptive defenses, do not make antibodies.
T lymphocytes
46
capability to respond to a specific antigen by binding to it with antigen-specific receptors that appear on the lymphocyte’s surface
immunocompetence
47
where T cells develop immunocompetence
thymus
48
Where B cells develop immunocompetence
bone marrow
49
help the lymphocytes but do not respond to specific antigens. - The cells engulf antigens and then present fragments of them on their own surfaces where they can be recognized by T cells.
antigen-presenting cells
50
when B cells encounter antigens and they produce antibodies
active immunity
51
antibodies are obtained from someone else
passive immunity
52
form antigen-binding sites, one on each arm of the T or Y
variable regions
53
determine the type of antibody formed (antibody class).
constant regions
54
Chief antibody ammunition against cellular antigens
complement fixation
55
Antibodies bind to specific sites on bacterial exotoxins or on viruses that can cause cell injury
neutralization
56
Antibody-antigen reaction that causes clumping of cell
agglutination
57
Cross-linking reaction in which antigen-antibody complex settles out of solution
precipitation
58
involves attracting immune cells, like the natural killer, which can kill the cell coated by antibodies.
Antibody-dependent cell-mediated cytotoxicity
59
engulfing or ingestion of the target cells.
phagocytosis
60
involves activating the complement, causing pores to appear in the membranes of the pathogens which allows water to go inside leading to bursting.
Complement-dependent cytotoxicity
61
fight antigens directly. Immunocompetent t cells are activated to make a clone by bonding by recognized antigens
t cells
62
produce toxic agents to kill their targets
cytotoxic T cells
63
Stimulate B cells to make antibodies and stimulate T cells to become active.
helper t cells
64
suppress immune responses
regulatory t cells
65
happens when a tissue is transplanted from one site to another on the same person.
autograft
66
when the tissue is transplanted from a genetically identical person (identical twin
isograft
67
when the tissue is taken other than an identical twin. Most common type of transplant.
allograft
68
when the tissue is taken from a different animal species. Up to date, there is no successful outcome
xenograft
69
abnormally vigorous immune responses. The immune system overreacts to a harmless antigen and tissue damage occurs.
allergies
70
occurs when the body’s self tolerance breaks down. The body produces auto-antibodies and sensitized T lymphocytes that attack its own tissues.
autoimmune diseases
71
may be congenital (patients lack the ability to produce an immune system) or acquired.
immunodeficiency