Lymphatic System Flashcards

(41 cards)

1
Q

What is the lymphatic system?

A
  • Series of vessels that carry excess tissue fluid to blood vessels near the heart, where the fluid enters the bloodstream
  • It is scattered throughout the body of the animal
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2
Q

Blood and lymph are carried into what?

A

Blood is carried in blood vessels, lymph is carried in lymphatic vessels

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3
Q

Lymph contains what?

A

Mostly lymphocytes, nutrients, hormones (+ substances that entered the tissue fluid that were carried in the plasma)

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4
Q

How are blood capillaries?

A

They are very porous; there is enough blood pressure in the blood capillaries for fluid to leave them

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5
Q

What will happen to the fluid?

A

Fluid will be drawn back; fluids naturally flow from the interstitial spaces into the blood vessels (osmotic pressure)

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6
Q

What is the problem with osmotic pressure?

A

Osmotic pressure from the venous side is not as strong as the blood pressure from the arterial side

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7
Q

What will lymph capillaries do to fix the problem of inequal osmotic pressure?

A

By taking up the excess fluid. The lymphatic system will bring back that fluid into the bloodstream through the thoracic duct (large lymph vessel)

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8
Q

What is capillary hydrostatic pressure?

A

Blood pressure on the capillary vessels

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9
Q

What is blood colloidal osmotic pressure?

A

Water pressure caused by the concentration of solutes in the blood

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10
Q

Body movements propel the lymph towards the heart with the help of what?

A

Valves that force a one-way movement of lymph in the vessels (no muscle cells to contract and to push lymph)

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11
Q

Where will the lymph empty?

A

In the superior vena cava before it enters the heart

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12
Q

What is the first function of the lymphatic system?

A
  • Removal of excess tissue fluid: fluid enters interstitial space containing nutrients, cells will pick up some of it, the rest should go into the lymphatic capillaries (if not, edema)
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13
Q

What is the second function of the lymphatic system?

A
  • Waste material transport: the interstitial fluid that enters the lymphatic capillaries will contain some of the waste from tissue cells
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14
Q

What is the third function of the lymphatic system?

A
  • Filtration of lymph: microorganisms, cellular debris and non-self molecules will enter the lymphatic system and be filtrated in the lymph nodes
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15
Q

What is the fourth function of the lymphatic system?

A
  • Lymph can pick up and transport into the blood circulation larger proteins (including enzymes) that can’t directly enter the bloodstream
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16
Q

What are the roles of lymph nodes?

A
  • Lymph from a specific area will always pass through the same lymph node
  • Lymph enters the lymph node from the afferent vessels and leave the node from the efferent vessels
  • Lymph node is divided into a cortex and a medulla
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17
Q

What is the structure of a lymph node?

A
  • Outer surface is called capsule
  • Cortex is where lymphocytes reside
  • Germinal centers: Stacked lymphocytes (also called lymph nodules)
  • Medulla is the skeleton of the lymph node and contains macrophages (phagocytosis)
18
Q

What is the spleen?

A
  • Spongelike organ that can store blood (soak-squeeze)
  • Largest lymphoid organ in the body, not essential for life
19
Q

What are the functions of the spleen?

A
  • Blood storage in the red pulp
  • Clean up non-self materials by macrophages
  • Removal of dead/defective red blood cells by macrophages
  • Lymphocytes cloning in the white pulp during immune response
20
Q

What will trabeculae do?

A

Squeeze out blood from the spleen because of smooth muscles

21
Q

Who have a more muscular trabeculae between carnivores and ruminants?

22
Q

In the spleen, where do lymphocytes reside?

A

In the white pulp, and they will multiply during an immune response

23
Q

What does red pulp contain?

A

Blood and macrophages

24
Q

What is the Thymus?

A

Lymphoid organ situated in the neck of vertebrates that produces T lymphocytes

25
What do thymocytes learn to distinguish?
Between self and non-self molecules before they are sent in the lymph nodes
26
What happens to the size of Thymus at the approach of puberty?
It becomes much smaller
27
Where are tonsils found?
In epithelial surfaces all over the body
28
What do tonsils prevent?
The spread of infection into the respiratory and digestive tracts
29
How are tonsils different that lymph nodes?
- Close to epithelial surfaces (mucosal) - Don't have a capsule - Beginning of lymph drainage, not along the lymph vessels
30
What is the function of the Immune system?
- Phagocytosis and destruction of foreign cells - Lysis of foreign cell membranes - Inactivation of foreign substances
31
Granulocytes are involved in what type of immunity?
Innate immunity
32
Lymphocytes are involved in what type of immunity?
Adaptive immunity
33
Monocytes are involved in what?
In making the link between the innate and adaptative immunities
34
What is nonspecific immunity? (innate)
- Provides the first line defense against pathogens - Acts very rapidly - Includes barriers such as the skin, molecules that are toxics to invaders, and phagocytic cells (phagocytes, such as macrophages) that ingest invaders - Recognizes broad classes of organisms or molecules and gives a quick response, within minutes or hours - Most animals have nonspecific defenses - Inflammation - Complement
35
What is specific immunity? (adaptive)
- Aimed at specific pathogens ` - A specific defense system that can make antibody proteins - These systems recognize specific configurations of atoms in a molecule - Typically slow to develop and long-lasting - Mechanisms found in vertebrate animals
36
What are the two types of specific immunity?
1. Cell-mediated immunity 2. Humoral immunity
37
What is cell-mediated immunity?
Immune response that involves T cells directly attacking infected or abnormal cells without the use of antibodies.
38
What is humoral immunity?
Immune response in which B cells produce antibodies that circulate in body fluids to neutralize pathogens.
39
What is an antigen?
Any molecule that serves as a target for the receptors of an adaptive immune response
40
Where can the antigen originate from?
May originate from within the body (self) or from the external environment (non-self)
41
What is the epitope?
An epitope is the specific part of an antigen that is recognized and bound by an antibody or a T cell receptor.