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Histology Lecture Test 2 > Lymphoid Tissue > Flashcards

Lymphoid Tissue Flashcards

1
Q

What is the largest lymphatic organ?

A

spleen (12cm long and 7cm wide)

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2
Q

Where is the spleen located?

A

-upper left quadrant of the abdomen
-lower than diaphragm
-ribs 9-11

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3
Q

What supplies the spleen?

A

Splenic artery and vein through hilum

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4
Q

Splenic artery is the ________ branch of the celiac artery

A

largest

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5
Q

What drains the splenic vein

A

inferior mesenteric vein

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6
Q

Spleens immune functions

A

-b and T cell replication
-removes aged or defective RBC’s
-recycles Fe and Hb
-hemopoiesis in fetus

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7
Q

If someone has a splenectomy (spleen removed)

A

liver and bone marrow will take over function of the spleen

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8
Q

Spleen lacks

A

cortex and medulla

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9
Q

Spleen has

A

-a capsule
-trabeculae

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10
Q

white pulp

A

-appears white/yellow
-both b and T cells

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11
Q

red pulp

A

-appears red
-full of blood
-70% of spleen

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12
Q

pulp cords

A

-within red pulp
-contain large # of lymphocytes and macrophages

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13
Q

sinusoids

A

-in red pulp
-contain mostly blood

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14
Q

Areas of white pulp in the spleen=

A

follicular areas
(some have germinal center some do not)

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15
Q

What is at the center of a follicle in the spleen?

A

Central Artery

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16
Q

Within the white pulp is a site of

A

-antigen presentation
-phagocytosis

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17
Q

What cells do you find in the white pulp?

A

macrophage
plasma cell
helper T cells

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18
Q

Splenic nodules

A

enlarged germinal center visible to the naked eye

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19
Q

What is PALS

A

-periarteriolar lymphatic sheaths
- T cells that surround the central artery
-not well developed in humans

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20
Q

Trabecular Artery of the spleen

A

-bloods enters the spleen through these
-branch into the central artery

21
Q

perpendicular penicillar Artery

A

-branch off of central artery

22
Q

open circulation in the spleen

A

perpendicular penicillin Artery dump blood into pulp cords

23
Q

closed circulation in the spleen

A

perpendicular penicillin Artery dump blood into the sinsusiod

24
Q

sheathed capillaries

A

-lack endothelial lining
-surrounded by macrophages

25
Q

What is the path of blood in the spleen

A

1.enters from the splenic artery
2. trabecular artery
3. central arterioles
4. penicillar arterioles
5.terminal capillaries
6. (open) pulp cords
7. splenic sinusoids
8. trabecular veins
9. splenic veins

26
Q

Stave Cells

A

-endothelial
-long cells that lie parallel to the long axis of the vessel
-helps to filter RBCs

27
Q

MALT structure

A
28
Q

What is the location of MALT?

A

-gastrointestinal
-respiratory
-genital
-urinary

29
Q

Function of MALT

A

-detect antigens
-initiate a response

30
Q

What are the 3 main Tonsils?

A

Palatine
Lingual
Pharyngeal

31
Q

Waldeyer’s Ring

A

where you find 3 main tonsils
-around open of mouth and nose

32
Q

Function of Waldeyer’s Ring

A

antibody production to common environmental antigens

33
Q

Tonsils are

A

-secondary lymphoid structure
-a type of MALT

34
Q

When you have your tonsils removed which one is taken out?

A

palatine

35
Q

Where are palatine tonsils located?

A

in tonsillar crypts

36
Q

Where is the lingual tonsil located?

A

back of the tongue

37
Q

Palatine Tonsil

A

crypts
1’ & 2’ follicle
no cortex or medulla

38
Q

Thymus

A

-Hassal’s corpuscle
-medula and cortex
-most t -cells not B cells

39
Q

pharyngeal tonsil (adenoids) are located

A

in nasopharynx

40
Q

Palatine Tonsil has scattered

A

lymphoid follices

41
Q

Tonsillar Crypt

A

-opening into the tonsil
-allows particles in so it can check it

42
Q

GALT

A

in gut

43
Q

BALT

A

repository track

44
Q

NALT

A

pharynx

45
Q

Dome areas

A

when lymphoid tissue of GALT projects into the lumen

46
Q

MALT produces

A

sIgA

47
Q

M cells

A

-in the gut
-have a lot of folds on surface
-sample Antigens and transfer from gut to lymphoid follicles

48
Q

When is MALT most abundant?

A

in childhood (get smaller with age)

49
Q

Appendix

A

-has a lot of B cells
-may have some role in antigen identification and developing antibodies

Histology Lecture Test 2 (12 decks)

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