Lymphoma 031121 Flashcards Preview

Scarlett's pathology flashcards > Lymphoma 031121 > Flashcards

Flashcards in Lymphoma 031121 Deck (17)
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1
Q

how do you diagnose and stage lymphoma

A

histological diagnosis, anatomical stage (CT, PET BM biopsy, LP). Bloods (LDH, albumen, kidney, HIV +Hep B serology)

2
Q

how are non hodgkins lymphomas divided

A

B cell, T cell, premature, mature, grade

3
Q

hodgkins lymphoma epidemiology

A

Male more than female, bimodal age incidence,

4
Q

how is hodkins lymphoma staged

A

ann-arbor, (one lymph node region, 2 lymph node regions, two LN regions on opposite sides of diaphragm, extranodal sites)

5
Q

hodgkins lymphoma diagnosis

A

CT PET, LN or BM biopsy, reed sternberg cells (owl eyes)

6
Q

treatment of hodgkins

A

chemotherapy, ABVD (ADRIAMYCIN, BLEOMYCIN, VINBLASTINE, DACARBAZINE), radiotherapy but gives breast cancer risk

7
Q

burkitts lymphoma translocation n

A

t(8;14)

8
Q

three types of burkitts

A

endemic, sporadic, immunodeficiency

9
Q

histology or burkitts

A

starry sky

10
Q

diffuse large b cell lymphona epidemiology

A

middle aged and elderly, aggressive, richters transformation other lymphomas occur secondary to it

11
Q

follicular lymphoma epidemiology

A

indolent, mostly incurable, median survival 12-15

12
Q

follicular lymphoma histology

A

follicular pattern, nodular appearance

13
Q

mantal cell lymphoma histology

A

angular nuclei

14
Q

most common subtype of HL

A

Nodular sclerosing is most common

mixed cellularity, lymphocyte rich, lymphocyte depleted

15
Q

monitoring is appropriate for which lymphoma

A

follicular

16
Q

CLL staging

A

binet

17
Q

CLL clinical features

A

symmetrical painless lymphadenopathy, BM failure, FLAWS (B symptoms), hepatosplenomegaly, associated with autoimmunity, can progress to lymphoma