Lymphoma

Question 1

Characterized by reed sternberg or owl eye cells

Answer 1

Hodgkins Lymphoma

Question 2

Chemotherapy regimen for Hodgkins

Answer 2

ABVD

Adriamycin Bleomycin Vincristine Dacarbazine

Question 3

Common side effect of bleomycin

Answer 3

Pulmonary toxicity

Question 4

What infectious agent predisposes to Gastric MALT lymphoma?

Answer 4

H pylori

Question 5

What infectious agent predisposes to multicentric Castlemans disease / primary effusion lymphoma?

Answer 5

Human herpesvirus 8 (HHV-8)

Question 6

What infectious agent predisposes to lymphoplasmacytic lymphoma?

Answer 6

Hepatitis C

Question 7

What infectious agent predisposes to Diffuse large B cell lymphoma and Burkitts or any Hodgkins Lymphoma?

Answer 7

HIV

Question 8

What infectious agent predisposes to adult T cell leukemia/lymphoma?

Answer 8

HTLV-1

Question 9

What infectious agent predisposes to Hodkins Lymphoma

Answer 9

EBV

Question 10

Cytogenetic translocation in Mantle cell lymphoma

Answer 10

t(11;14)

Question 11

Cytogenetic translocation in follicular lymphoma

Answer 11

t(14;18)

Question 12

Cytogenetic translocation in anaplastic lymphoma

Answer 12

t(2;5)

Question 13

Cytogenetic translocation in burkitts lymphoma

Answer 13

t(8;14)

Question 14

Smudge or basket cells

Answer 14

B cell CLL / small lymphocytic lymphoma

Question 15

CD5 Positive lymphomas are:

Answer 15

Mantle cell lymphoma
B cell CLL
Lymphoplasmacytic lymphoma

Question 16

Most common treatment of B cell CLL

Answer 16

Chlorambucil or Fludarabine / Bendamustine

Question 17

CD5 Negative lymphomas

Answer 17

MALT lymphoma

Question 18

Treatment of MALT?

Answer 18

Single agent chlorambucil

Eradication of H pylori

Question 19

Most common presentation of mantle cell lymphoma

Answer 19

Palpable lymphadenopathy

Lymphomatosis polyposis in the large intestines with Waldeyer ring involvement

Question 20

Treatment of Mantle cell lymphoma?

Answer 20

HyperC-VAD
R-HyperC-VAD

Rituximab + Cyclophosphamide Vincristine Doxorubicin Dexamethasone Cytarabine Methotrexate

Question 21

Double hit lymphomas MYC and BCL6

Answer 21

Diffuse B cell lymphoma

Question 22

Starry sky appearance

Answer 22

Burkitts lymphoma

Question 23

The most rapidly progressing tumor that always needs CSF examination to rule out mets

Answer 23

Burkitts lymphoma

Question 24

When should treatment for burkitts start?

Answer 24

Treatment for both children and adults should be started within 48 hours of diagnosis
High dose cyclophosphamide

Question 25

Hairy cell leukemia have monocytopenia and are prone to infections to

Answer 25

Mycobacterium avium intracellulare

Question 26

Indolent mature T cell lymphoma with eczematous skin lesions

Answer 26

Mycosis fungoides

Question 27

Sezary syndrome

Answer 27

Mycosis fungoides or cutaneous T cell lymphoma

Question 28

Tropical spastic paraparesis is a presentation of what lymphoma

Answer 28

Adult T cell lymphoma

Question 29

Flower cells

Answer 29

Adult T cell lymphoma HTLV 1

Question 30

Has best survival rate among any aggressive lymphoma

Answer 30

Anaplastic large T cell lymphoma

Question 31

Treatment of anaplastic T cell lymphoma?

Answer 31

Same as any aggressive lymphoma but rituximab is omitted

Question 32

Pattern of fever in Hodgkins lymphoma

Answer 32

Pel Ebstein fever

Question 33

Popular chemotherapy regimen for Hodgkins

Answer 33

ABVD | Doxo Bleo Vincristine Dacarbazine

Question 34

Electric shock sensation into the lower extremities upon flexion of the neck in patients receiving thoracic radiotherapy

Answer 34

Lhermitte's syndrome

Question 35

Lymphoma-like disorder presenting as bulky lymphadenopathy which is non progressive and self limiting

Answer 35

Rosai Dorfman syndrome