(M) Donor Selection Flashcards
1
Q
familiarize the regulating agencies / accreditation
A
- CFR (code of federal regulations)
- CBER (Center for Biologics Evaluation and Research)
- AABB (American Association of Blood Banks)
- CMS (Centers for medicare and medicaid services)
- CLIA ‘88 (Clinical Laboratory Improvement Amendments of 1988)
- CAP (College of American Pathologists)
2
Q
Definition of terms
regular donation; collected blood use for transfusion of another patient or individual
A
allogeneic donation
3
Q
Definition of terms
The one who donates blood for his or her own use
A
Autologous Donation
4
Q
Definition of terms
Same with allogeneic but unit collected is directed towards a specific patient
A
Directed Donation
5
Q
Definition of Terms
Desired component of blood collected and centrifuged, and remaining elements subsequently returned to the donor
A
Apheresis Donation
6
Q
Steps in blood donation
Step 1 : Donor registration
1. ____ ID
2. Donor fills up the donor ____.
3. Should fully identify the donor & link the donor to existing ____.
A
- Picture ID
- donor fills up the donor form
- Should fully identify the donor & link the donor to existing records
7
Q
Donor history questionnaire form
- ____ personal information / data
- Medical ____ questions
- ____ awareness
- Donor’s informed ____
- Confidential Unit ____
- ____ Examination
- This can be ____ or by a trained donor historian
A
- Donor personal information / data
- Medical history questions
- AIDS awareness
- Donor’s informed consent
- Confidential Unit exclusion
- Physical Examination
- This can be self administered or by a trained donor historian
8
Q
Step 2: Donor Selection & Screening
(enumerate the two steps)
A
a. Interview and Physical Examination
b. Pre-donation testing
9
Q
Step 2: Donor selection and screening
- First Step in ensuring safety of our blood supply?
- What are the two considerations?
A
- Interview and physical exam
- Safe for the donor and beneficial to the recipient
10
Q
Step 2: Donor Selection and Screening
Pre-donation counseling
1. ____ history assessment
2. knowledge of ____ and other ____
3. Donation information
4. ____ factor and knowledge
A
- Risk history assessment
- knowledge of HIV and other TTIs
- Donation information
- Psychosocial factor and knowledge
11
Q
Step 2: Donor selection and screening
- Age limit for donors?
- Temperature?
- Pulse?
A
- 16 years and above (no upper age limit)
- ≤ 37.5 C
- 50-100 bpm
12
Q
Step 2: Donor selection and screening
- Weight
- Hgb
* Women
* Men - Hct
* Women
* Men
A
1.equal to or more than 50 kg
2.Hgb
* Women : ≥ 12.5 g/dL
* men: ≥13 g/dL
3.Hct
* Women: ≥38%
* Men: ≥39%
13
Q
Hgb maximum values
A
- Women : 17.2 g/dL
- Men: 18.5 g/dL
14
Q
study the computation of the maximum draw for donors weighing less than the ideal weight (50kg)
A
Gaur
15
Q
Types of donor deferral
- donor is unable to donate blood for a limited (specified) period of time
- Donor will never be eligible to donate blood
- Donor is unable to donate blood for an unspecified
A
- Temporary deferral
- Permanent deferral
- Indefinite deferral
16
Q
Timing of donation or deferral
Antihistamine, Analgesic, Bronchodilators, Contraceptives, Decongestant, Food supplements, NSAID (except for platelet prep), Vitamins, Topical steroids
A
Anytime
17
Q
Timing of donation or deferral
Anticonvulsant, betablockers, digitalis, growth hormone, psoriasis treatment, Tegison / etretinate psychosis drugs, insulin
A
permanent
18
Q
Timing of donation or deferral
Antibiotic (after end of treatment), Proscar, Propecia, Acutane
A
one month
19
Q
Timing of donation or deferral
Dutasteride / avodart (BPH)
A
6 months
20
Q
Timing of donation or deferral
Anti-platelet activity
1. Feldene
2. Aspirin
3. Plavix / Ticlid
A
- 2 days
- 3 days
- 14 days
21
Q
Timing of donation or deferral
- Soriatane
- Glutathione as prep for liver disorder
- Glutathione for cosmetics use
- Anti-hypertensive drugs
A
- 3 years
- permanent
- 1 year
- temporary (needs medical clearance)
22
Q
Timing of donation or deferral
- COVID-19 Vaccine
- Killed toxoids or synthetic viral / bacterial / rickettsial vaccine
- Hepa A (non-exposure)
- Hepa A (w/ close contact)
A
- 14 days
- No deferral (anytime)
- Anytime
- 6 weeks
23
Q
Timing of Donation / Deferral
- Tetanus immunoglobulin
- Rabies (post-exposure / bite)
- Hepa B (non-exposure)
- Hepa B (w/ close contact)
A
- one year from last dose
- one year from last dose
- 1 week after vaccination
- one year
24
Q
Timing of Donation / Deferral
- Allogeneic whole blood donation (single unit)
- Allogeneic whole blood donation (two units of RBC donation)
A
- ≥ 8 weeks
- ≥ 16 weeks
25
# timing of Donation / Deferral
Apheresis
1. platelet
2. Plasma (occasional)
3. Plasma (Serial)
4. Granulocyte
5. Double RBC autologous / allogenic
1. 48 hrs
2. 4 weeks
3. 48 hours
4. 48 hours
5. 16 weeks
26
# Timing of donation / deferral
1. Pregnancy (existing / 6 weeks)
2. Pregnancy (miscarriage / abortion)
3. Malaria (lives in an endemic area)
4. Previously diagnosed with malaria (done with treatment, symptom-free)
5. History of travel from a malaria endemic area
6. Surgery, Blood transfusion, tooth extraction, tattoo, ear piercing, acupuncture, close contact w/ a person w/ hepatitis, incarcerated receipt of clotting factors
1. 6 weeks after delivery / 3 weeks after weaning
2. accept
3. 3 years
4. 3 years
5. 12 months
6. 12 months
27
# Timing of donation / deferral based on HARMENING
1. CHD, CVD, RHD
2. Confirmed positive for HBsAg, anti-HBc, anti-HCV, HTLV 1/2, HIV
3. Cancer, leukemia, lymphoma
4. IV drug users
5. Blood diseases, hemophilia, SCA, kAPOSIS, Thalassemia, PCV
1. deffered ; if without disability may be accepted
2-5. Indefinite
28
# Timing of donation / deferral based on the A-Z guide DOH
1. CHD, CVD, RHD
2. Confirmed positive for HBsAg, anti-HBc, anti-HCV, HTLV 1/2, HIV
3. Cancer, leukemia, lymphoma
4. IV drug users
5. Blood diseases, hemophilia, SCA, kAPOSIS, Thalassemia, PCV
1. PERMANENT
2. PERMANENT
3. PERMANENT
4. INDEFINITE
5. PERMANENT
29
# Timing of donation / deferral based on HARMENING
1. Sexual contact with anyone with HIV/AIDS positive individuals
2. Female who had sex with men who had MSM
3. Treated for STD such as syphilis and gonorrhea
1. 12 months
2. 12 months
3. 12 months after completion of therapy
30
# Timing of donation / deferral based on DOH
1. Sexual contact with anyone with HIV/AIDS positive individuals
2. . Female who had sex with men who had MSM
3. Treated for STD such as syphilis and gonorrhea
1. indefinite
2. indefinite
3. permanent
31
# timing of donation / deferral based on HARMENING
1. MSM anytime since 1977
2. Casual sex, sex with IVD user, sex for money / drugs
3. From Central African Republig, Negeria, Chad, Congo, Gabon, Camerron
1. Permanent
2. Permanent
3. Indefinite
32
# Timing of Donation / Deferral based on the A-Z guide (DOH)
1. MSM anytime since 1977
2. Casual sex, sex with IVD user, sex for money / drugs
3. From Central African Republig, Negeria, Chad, Congo, Gabon, Camerron
1-3. Indefinite
33
# Step 2: Donor selection
What are the two tests done during the pre-donation testing
1. ABO slide / tube method
2. Hemoglobin
34
# Step 2: Donor Selection
What are the two possible methods of hemoglobin testing for the pre-donation testing?
1. Copper sulfate
2. automated analyzer
35
# Step 3: Donor phlebotomy
1. Use ____ technique
* 70 % ____ alcohol
* ____ compound
. Use **aseptic** technique
* 70 % **isopropyl** alcohol
* **Iodophor** compound
36
# Step 3: Bleeding / phlebotomy
1. when do you label the blood bag
2. Ask donor to open and close hand every ____ seconds
3. Mix blood periodically every ____ seconds
4. Fill ____ tubes
1. during collection
2. 10-12 seconds
3. 45 seconds
4. pilot tubes
37
# Step 3 : bleeding / phlebotomy
1. volume of a standard blood bag
2. low volume range for a 450 mL bag
3. low volume range for a 500 mL bag
1. 450 mL
2. 300 - 404
3. 333 - 449
38
# Step 3: donor phlebotomy
1. tool used to mix blood from the segment with AC in the mother bag
2. tool used to keep a close system / hermetic seal
1. tube stripper
2. automatic tube sealer
39
# ```
```
What are included in the post donation screening?
1. ABO
2. Antibody
40
What are the 5 TTIs
1. HIV
2. HEPA-B
3. HEPA-C
4. SYPHILIS
5. MALARIA
41
Mild, severe, or moderate?
1. syncope
2. decreased pulse
3. hyperventilation
4. vasovagal syncope
5. Twitching / muscle spasm
1. mild
2. moderate
3. moderate
4. severe
5. mild
42
Mild, Moderate, Severe?
1. loss of consciousness
2. shock
3. marked hyperventilation
4. Vomitting
5. fall in systolic bp
1. mild
2. severe
3. severe
4. mild
5. moderate
43
# Matching type
1. Weakness, sweating dizziness, pallor, nausea and vomiting
2. syncope
3. twitching, muscle spasm
a. cold compress on back of neck
b. Remove needle and tourniquet, elevate legs above head, apply cold compress to forhead and back of neck
c. have donor cough
1. b
2. a
3. c
44
# Maching type
1. Convulsion
2. Hematoma
3. Cardiac difficulties
a. apply pressure for 7-10 minutes, apply ice to area for 5 minutes
b. begin cardiopulmonary resuscitation, call for help emergency
c. call for help, prevent donor from falling from donor chair to prevent injury, ensure donor's airway is adequate
1. C
2. A
3. B
45
# AUTOLOGOUS DONATION
familiarize the 4 collections
1. preoperative collection
2. acute normovolemic hemodilution
3. intraoperative collection
4. postoperative collection
46
# Autologous donation
Preoperative collection
1. Hgb =
2. Hct =
3. Last donation must be within ____ hrs before surgery
4.ABO Rh is (required / not required)
5. Distinct label =
6. TTI is only if to be transfused ____ the collecting facility
Preoperative collection
1. Hgb = **11 g/dl**
2. Hct = **33%**
3. Last donation must be within **72** hrs before surgery
4. ABO Rh is **mandatory**
5. Distinct label = **for autologous use only**
6. TTI is only if to be transfused **outside** the collecting facility
47
# Autologous Donation
Acute normovolemic hemodilution (ANH)
1. WB is removed, replaced with ____ / colloid before surgical blood loss
2. Indication =
3. Label =
4. Storage: ____ hrs RT ; 24 hrs ____C
5. Reinfusion (shed blood) is done on ____ order. last unit with the highest HCT
1. WB is removed, replaced with **crystalloids** / colloid before surgical blood loss
2. Indication : **surgical blood loss**
3. Label = **For autologous use only**
4. Storage: **8** hrs RT ; 24 hrs **1-6C**
5. Reinfusion (shed blood) is done on **reverse** order. last unit with the highest HCT
48
# Autologous donation
Intraoperative collection
1. collecting and reinfusing blood lost during ____
2. Indication: cardiac, cardiothoracic, vascular major orthopedic surgery
3. Label:
4. Storage : ____ hrs RT; 24 hrs ____C
5. Risk =
1. collecting and reinfusing blood lost during **surgery**
2. Indication: cardiac, cardiothoracic, vascular major orthopedic surgery
3. Label: **for autologous use only**
4. Storage : **6** hrs RT; 24 hrs **1-6**C
5. Risk = **DIC**
49
# Autologous donation
Post operative blood collection
1. blood is collected from a drainage tube at the ____
2. Indication:
3. Storage : ____ hrs RT; 24 hrs ____
4. Reinfused without processing; volume no more than ____
1. blood is collected from a drainage tube at the **surgical site**
2. Indication: c**ardiac and orthopedic surgery**
3. Storage : **6** hrs RT; 24 hrs **1-6C**
4. Reinfused without processing; volume no more than **1400 mL**
50
# Step 4: post donation processing
What are the four components?
1. whole blood / red cell components
2. platelet concentrate
3. Fresh Frozen plasma
4. cryoprecipitate
51
Arrange the following from the first to the last step
a. Post-donation care
b. Donor selection and screening
c. Donor Phlebotomy
d. Donor Registration
d, b, c, a
